人物履历
1995 年于中国科学院上海药物研究所获博士学位,留所任助理研究员;1996 年赴日本九州大学药学部生药学教室进行博士后工作;
1998 年回所工作,期间曾赴美国加州大学圣地亚哥分校 Scripps 海洋学研究所访问研究。
研究方向
以产业化为目标,以天然药用资源的水溶性成分研究为基础,探索中药的作用机理和物质基础,寻找和发现结构新颖的天然活性化合物及先导化合物,并在此基础上开展新药创制和中药现代化的研究。
承担科研项目情况
承担“重大新药创制”国家科技重大专项,上海市重大产业科技攻关项目等多个课题。
获奖及荣誉
2011年获国家技术发明二等奖
2011年获中国药学发展奖杰出青年学者奖
2007年获上海市技术发明一等奖
2006年获中国国际工业博览会创新奖
2006年获上海市科教党委系统青年科技创新人才奖
2005年获中国科学院先进集体2004年获上海药学会药学科技奖
2020年11月24日,获得全国先进工作者荣誉称号。[1]
代表论著
Xiao-Ping Hu, Shu-Wei Zhang, Shan-Shan Liu, and Li-Jiang Xuan. New Anthraquinone and Iridoid Glycosides from the Stems of Hedyotis hedyotidea. Helvetica Chimica Acta
Zhou Tong; Zhang Xiao-Hui; Zhang Shu-Wei; Liu Shan-Shan; Xuan Li-Jiang. New Phenylpropanoids and In Vitro α-Glucosidase Inhibitors from Balanophora japonica. Planta medica
Zhou, Tong; Zhang, Shu-wei; Liu, Shan-shan; Cong, Hai-jian; Xuan, Li-jiang. Daphnodorin dimers from Edgeworthia chrysantha with α-glucosidase inhibitory activity. Phytochemistry Letter
Chen, Li; Xuan, Li-Jiang; Wang, Yi-Ping. Effects of magnesium lithospermate B and its analogues on Ca2+ homeostasis in cultured rat thoracic aorta vascular smooth muscle cells. Planta Medica
Yu, Juan; Zhang, Hao-Hao; Yu, Qiang; Xuan, Li-Jiang. Prenylated Phenols from Sabia japonica. Helvetica Chimica Acta
Liu, Shan-Shan; Zhou, Tong; Zhang, Shu-Wei; Xuan, Li-Jiang. Chemical Constituents from Clerodendrum bungei and Their Cytotoxic Activities. Helvetica Chimica Acta
Zhang, Xiao-Hui; Liu, Shan-Shan; Xuan, Li-Jiang. Cyclopentenylglycines and other constituents from Alangium chinense. Biochemical Systematics and Ecology
Wu, Jun; Zhou, Tong; Zhang, Shu-wei; Zhang, Xiao-hui; Xuan, Li-jiang. Cytotoxic terpenoids from the fruits of Vitex trifolia L. Planta Medica
Xiao Kai, Zhang Hongjun, Xuan Lijiang, Zhang Juan, Xu Yaming, Bai Donglu. Stilbenoids: chemistry and bioactivities. Studies in natural chemistry
Xiaohui Zhang, Shuwei Zhang, Lijiang Xuan. Three new furannosesquiterpenoids from Bombax malabaricum and revised NMR assignment of Hibiscone C. Heterocycles
Shanshan Liu, Huilin Zhu, Shuwei Zhang, Xiaohui Zhang, Qiang Yu, and Lijiang Xuan. Abietane diterpenoids from Clerodendrum bungei. J. Nat. Prod
Jun Wu, Xiaohui Zhang, Shuwei Zhang, Lijiang Xuan. Three novel compounds from the flowers of Bombax malabaricum. Helvertica Chimica Act
Wang, Li; Zhang, Qiang; Li, Xiaochuan; Lu, Youli; Xue, Zhimou; Xuan, Lijiang; Wang, Yiping. Pharmacokinetics and metabolism of lithospermic acid by LC/MS/MS in rats. International Journal of Pharmaceutics
Shuwei Zhang, Lijiang Xuan. Cyclopentenone and furan derivative from mycelia of Cordyceps cicadae. The Journal of Antibiotics
Zhang, Xiao-Hui; Zhu, Hui-Lin; Yu, Qiang; Xuan, Li-Jiang. Cytotoxic cardenolides from Streptocaulon griffithii. Chemistry & Biodiversity
Zhang, Shu-Wei; Xuan, Li-Jiang. Five aromatics bearing a 4-O-methylglucose unit from Cordyceps cicadae. Helvetica Chimica Acta,
Jiang, Lili; Zhang, Shuwei; Xuan, Lijiang. Oxanthrone C-glycosides and epoxynaphthoquinol from the roots of Rumex japonicus. Phytochemistry
Zhang, Xiaohui; Zhu, Huilin; Zhang, Shuwei; Yu, Qiang; Xuan, Lijiang. Sesquiterpenoids from Bombax malabaricum. Journal of Natural Products,
Li, Xiaochuan; Yu, Chen; Wang, Li; Lu, Youli; Wang, Wenyi; Xuan, Lijiang; Wang, Yiping. Simultaneous determination of lithospermic acid B and its three metabolites by liquid chromatography/tandem mass spectrometry. Journal of Pharmaceutical and Biomedical Analysis
Li, Xiaochuan; Yu, Chen; Lu, Youli; Gu, Yunlong; Lu, Jie; Xu, Wei; Xuan, Lijiang; Wang, Yiping. Pharmacokinetics, tissue distribution, metabolism, and excretion of depside salts from Salvia miltiorrhiza in rats. Drug Metabolism and Disposition
参考资料 1
- 上海市112名全国劳模和先进工作者揭晓,平均年龄48岁 — 澎湃新闻