游静,1974年10月生,1996年毕业于长春地质学院应用化学专业,2000年在中国科学院兰州化学物理研究所获得分析化学博士学位。之后在美国南伊利诺伊州立大学化学系和动物系从事分析化学与环境毒理学的研究,2006年任南伊利诺伊州立大学动物系兼职研究生导师,2007年任美国中密苏里州立大学生物化学、化学与物理系助理教授。2008年入选中国科学院“百人计划”,并与2009年1月正式到位工作。现任中国科学院研究员。
学术研究
主要从事沉积物中有机污染物(新兴农药与其它持续性有机污染物)的分布、生物有效性、生态毒性和毒理动力学以及混合污染物的毒性评价和鉴定的研究。近年来在沉积物中拟除虫菊酯类农药残留的分布及其对底栖无脊椎动物的毒性效应与毒理动力学方面进行了大量研究,其中该类农药对城市区域中水体环境评价的研究被国际环境科学界权威杂志Environmental Science & Technology(ES& T)作为封面文章进行了专门报道。在国际SCI杂志ES & T, Environmental Toxicology & Chemistry, Chemosphere 和Journal of Chromatograph A等上发表论文31篇,其中第一作者16篇。目前的工作重点在沉积物中有机污染物生物有效性和毒性评估研究。
教育背景
科研经历
2002至2007年在美国南伊利诺伊州立大学化学系和动物系任博士后研究人员、助理科学家、副科学家、研究顾问和兼职研究生导师(至今),从事液相色谱检测器研制以及水生毒理学研究。
2007至2008年在美国中密苏里州立大学化学系任助理教授,从事有机污染物环境行为和生物可利用性研究。
2009年获中科院“百人计划”项目支持到广州地化所工作。
研究领域
环境地球化学、生态毒理学(沉积物生态风险评价)
获奖及荣誉
2010年,中国科学院广州分院、广东省科学院“优秀青年科技工作者”;
2011年,国际环境毒理与化学协会(SETAC)与英国皇家化学协会(RSC)联合颁发的2011年度“SETAC/RSC奖”,该奖项由国际环境毒理与化学协会与英国皇家化学协会联合颁发,每年奖励一名在环境科学方面做出突出成果的、40岁以下的青年科研人员;
2012年,获国家基金委地学部“优秀青年基金”资助。
代表论著
1. Du J., Pang J.-X., You J*. Bioavailability-based chronic toxicity measurements of permethrin to Chironomus dilutus. Environ. Toxicol. Chem.
2. Li H.-Z., Sun B.-Q., Chen X., Lydy M.J., You J.* Addition of contaminant bioavailability and species susceptibility to a sediment toxicity assessment: Application in an urban stream in China, Environ. Pollut.
3. Li H.-Z., Sun B.-Q., Lydy M.J., You J*. Sediment-associated pesticides in an urban stream in Guangzhou, China: Implication of a shift in pesticide use patterns. Environ. Toxicol. Chem
4. Li Y.-L., Fang Z.-X., You J*. Application of Box-Behnken Experimental Design to optimize the extraction of insecticidal Cry1Ac from soil, J. Agric. Food Chem., 2013, 61, 1464-1470.
5. Ding Y.-P., Landrum P.F., You J.*, Lydy M.J.* Assessing bioavailability and toxicity of permethrin and DDT in sediment using matrix solid phase microextraction. Ecotoxicology
6. Pang J.-X., Sun B.-Q., Li H.-Z., Mehler W.T., You J*. Influence of bioturbation on bioavailability and toxicity of PAHs in sediment from an electronic waste recycling site in South China. Ecotox. Environ. Saf.
7. Wang J.-Z., Li H.-Z., You J.* Distribution and toxicity of current-use insecticides in sediment of a lake receiving waters from areas in transition to urbanization, Environ. Pollut
8. Du J., Mehler W.T., Lydy M.J., You J. * Toxicity of sediment-associated unresolved complex mixture and its impact on bioavailability of polycyclic aromatic hydrocarbons, J. Hazard. Mater
9. Mehler W. T., Li H.-Z., Lydy M. J., You J.* Identifying the causes of sediment-associated toxicity in urban waterways of the Pearl River Delta, China. Environ. Sci. Technol
10. Mehler W.T., Du J., Lydy M.J., You J.* Joint toxicity of a pyrethroid insecticide, cypermethrin, and a heavy metal, lead, to the benthic invertebrate Chironomus dilutus. Environ. Toxicol. Chem
11. You J.*, Harwood A. D., Li H.-Z., Lydy M. J. Chemical techniques for assessing bioavailability of sediment- associated contaminants: SPME versus Tenax extraction. J. Environ. Monit
12. Li H.-Z., Bai J.-M., Li Y.-T., Cheng H.-F., Zeng E. Y., You J.* Short-range transport of contaminants released from e-waste recycling site in South China. J. Environ. Monit
13. Yan Y., Yang Y., You J.*, Yang G., Xu Y., Huang N., Wang X., Ran D., Yuan X., Jin Y., Fan Y., Lei J., Li W., Gu H.*, Permethrin modulates cholinergic mini-synaptic currents by partially blocking the calcium channel. Toxicol. Lett
14. Mehler W. T., Li H.-Z., Pang J.-X., Sun B.-Q., Lydy M. J., You J.*. Bioavailability of hydrophobic organic contaminants in sediment with different particle size distributions. Arch. Environ. Contam. Toxicol.
15. Ding Y.-P, Weston D. P., You J.*, Rothert A. K., Lydy M. J., Toxicity of sediment-associated pesticides to Chironomus dilutus and Hyalella azteca. Arch. Environ. Contam. Toxicol
16. You J., Kelley R., Crouse C., Trushenski J.T., Lydy M.J. Analysis of persistent halogenated hydrocarbons in fish feeds containing fish oil and other alternative lipid sources. Talanta
17. H.-Z. Li, W. T. Mehler, M. J. Lydy, J. You*. Occurrence and distribution of sediment-associated insecticides in urban waterways in the Pearl River Delta, China. Chemosphere
18. H.-Z. Li, W.-L. Wei, J. You*, M. J. Lydy, Analysis of sediment-associated insecticides using ultrasound assisted microwave extraction and gas chromatography-mass spectrometry. Talanta
19. Pehkonen S., You J.*, Akkanen J., Kukkonen J.V.K., Lydy M.J. Influence of black carbon and chemical planarity on bioavailability of sediment-associated contaminants. Environ. Toxicol. Chem
20. Wang D., You J.*, Lydy M.J. Sediment matrix effects in quantitative analysis of pyrethroid insecticides using gas chromatography-quadrupole mass spectrometer. Arch. Environ. Contam. Toxicol.
21. Mehler W.T., You J.*, Maul J. D., Lydy M.J. Comparative analysis of whole sediment and pore water toxicity identification evaluation techniques for ammonia and nonpolar organic contaminants. Chemosphere
22. You J., Wang D., Lydy M.J. Determination of pyrethroid insecticides in sediment by gas chromatography – ion trap tandem mass spectrometry. Talanta
23. Ding Y.-P, You J.*, Lydy M.J. Analysis of pyrethroid insecticides in Chironomus dilutus using matrix solid phase dispersion extraction. Bull. Environ. Contam. Toxicol
24. You J., Brennan A.A., Lydy M.J. Bioavailability and biotransformation of sediment- associated pyrethroid insecticides in Lumbriculus variegatus, Chemosphere