郝彦玲,女,中国农业大学食品科学与营养工程学院副教授,博士,博士生导师,农业部现代奶业产业技术体系专家组成员。主要从事乳酸菌遗传与代谢领域研究。
学习工作经历
2001年2月:哈尔滨商业大学食品科学专业获硕士学位。
2004年6月:中国农业大学食品科学专业获博士学位。
2008.1-2008.3:美国麻省大学短期访问。
2004.7-至今:在中国农业大学食品科学与营养工程学院工作。
2012.6-2013.6:荷兰瓦赫宁根大学访问学者,师从Willlem M devos教授。
教学工作
社会兼职
农业部奶业产业化专家组成员。
研究方向
(1)特质功能乳酸菌的高通量筛选及次级代谢产物表达调控研究
(2)乳酸菌胁迫应答机制的研究
(3)乳酸菌发酵制品及微生态制剂的开发
(4)利用基因工程技术生产酶制剂
科研课题
主持在研项目包括:
主持国家自然基金项目“植物乳杆菌素BM-1的结构鉴定及抑菌机制研究”1项;教育部新世纪优秀人才支持计划项目“保加利亚乳杆菌保加利亚乳杆菌CAUH1酸胁迫应答机制研究”1项。
参与的在研项目:
十二五农村领域国家科技计划课题“传统发酵乳制品微生物资源开发与产业化关键技术”,公益性行业(农业)科研专项经费项目“传统乳制品现代化生产技术研究与示范”和十二五农村领域国家科技计划课“安全高效饲料添加剂创制与应用”等6项
主要学术论文与获奖
代表性文章
1.Zhai, Z., Douillard, F.P., An, H., Wang, G., Guo, X., Luo, Y., and Hao, Y*. Proteomic characterization of the acid tolerance response in Lactobacillus delbrueckii subsp. bulgaricus CAUH1 and functional identification of a novel acid stress-related transcriptional regulator Ldb0677. Environmental Microbiology: published online: 17 OCT 2013, DOI:10.1111/1462-2920.12280. (IF: 5.943)
2.Feng Zhao, Xiufang Bi, Yanling Hao*, Xiaojun Liao*. Induction of Viable but Nonculturable Escherichia coli O157:H7 by High Pressure CO2 and Its Characteristics. PLOS ONE. 2013,8(4),e62388 (IF: 4.244)
3.Yanling Hao1, Dawei Huang1, Huiyuan Guo, Man Xiao, Haoran An, Zhao Liang, Fanglei Zuo, Zhang Bing, Songnian Hu, Shuhui Song, Shangwu Chen, Fazheng Ren. Complete Genome Sequence of Bifidobacterium longum subsp. longum BBMN68, a New Strain from a Healthy Chinese Centenarian. Journal of Bacteriology, 2011,193 (3):787-788. (1These authors contributed equally to this work). ( IF: 3.593)
4.Yin Sheng, Zhengyuan Zhai, Guohong Wang, Haoran An, Yunbo Luo, Yanling Hao*. A novel vector for lactic acid bacteria that uses a bile salt hydrolase gene as a potential food-grade selection marker. Journal of Biotechnology, 2011,152: 49-53. (IF: 3.34)
5.Haoran An, Zhengyuan Zhai, Sheng Yin, Yunbo Luo, Benzhong Han and Yanling Hao*.Coexpression of the superoxide dismutase and the catalase provides remarkable oxidative stress resistance in Lactobacillus rhamnosus. Journal of Agricultural and Food Chemistry,2011,59:3851-3856. ( IF: 3.288)
6.Xie Ying, Haoran An, Yanling Hao*, Qianqian Qin, Ying Huang, Yunbo Luo, Liebing Zhang*. Characterization of an anti-Listeria bacteriocin produced by Lactobacillus plantarum LB-B1 isolated from koumiss, a traditionally fermented dairy product from China. Food Control, 2011, 22: 1027-1031. (IF: 3.006)
7.Yanling Hao, Zhao Lu, Hongxing Zhang, Zhengyuan Zhai, Huang Ying, Xiaohui Liu, Liebing Zhang. Identification of the bacterial biodiversity in koumiss by denaturing gradient gel electrophoresis and species-specific polymerase chain reaction. Journal of Dairy Science ,2010,93:1926-1933. ( IF: 3.009)
8.Huang Ying, Yunbo Luo, Zhengyuan Zhai, Hongxing Zhang, Chaoxiang Yang, Hongtao Tian, Li Zheng, Jiannan Feng, Liu Hui, Yanling Hao*. Characterization and application of an anti-Listera bacteriocin produced by Pediococcus pentosaceus 05-10 isolated from Sichuan Pickle, a traditionally fermented vegetable product from China. Food Control, 2009, 20: 1030-1035. (IF: 3.006)
9.Guohong Wang, Sheng Yin, Haoran An, Shangwu Chen, Yanling Hao*.Coexpression of bile salt hydrolase gene and catalase gene remarkably improves oxidative stress and bile salt resistance in Lactobacillus casei. Journal of industrial microbiology and biotechnology, 2011, 38:985-990. (IF: 2.725)
10.Qianqian Qin, Bingshu Xia, Yao Xiong, Shixiang Zhang, Yunbo Luo, YanLing Hao*. Structural Characterization of the Exopolysaccharide Produced by Streptococcus thermophilus 05-34 and ItsIn Situ Application in Yogurt. Journal of food science , 2011,76(9):C1226-1230. ( IF: 2.16)
授权专利
奖励及其它
2010年校级优秀教师,2005年获中国农业大学第五届青年教师基本功比赛“三等奖”,2007,2008,2010三年皆获“百篇优秀毕业设计(论文)”优秀指导教师奖”,2008年获校级URP优秀指导教师奖。