杨燕

杨燕，中山大学公共卫生学院教授/博士生导师 /副院长。

教授/博士生导师 /副院长

学位/学历

博士（中山大学）

工作经历

2017/06—至今 中山大学，公共卫生学院（深圳）营养与食品卫生学系

2013/01—2014/01 江西省疾病预防控制中心，副主任（中组部博士服务团挂职）

2009/11—2011/09 加拿大多伦多大学病理生理系博士后

2005/07—2017/06 中山大学，公共卫生学院营养学系

营养与慢性非传染性疾病、血栓性疾病；

营养流行病学；

食品安全

迄今，作为项目负责人共主持国家自然科学基金面上项目4项，多项教育部、广东省自然科学基金、广东省科技厅等省部级纵向科研项目以及多项横向科研项目，指导本科生完成国家级、省级和校级大学生创新项目以及中山大学实验室开放基金等多项学生科研项目。

1. 2018年度国家自然科学基金面上项目，辅酶Q10经血小板整合素αIIbβ3改善糖脂代谢紊乱的作用及机制研究，主持。

2. 2017年度国家自然科学基金重点项目，膳食花色苷gān及白藜芦醇改善糖脂代谢紊乱摄入量－效应研究，参加

3. 2015年度国家自然科学基金面上项目，花色苷对血小板趋化因子调节动脉粥样硬化炎症反应的影响及机制研究，主持。

4. 2013年度国家自然科学基金面上项目，花色苷经血小板凋亡途径抗动脉粥样硬化的研究，主持。

1. F. L. Ya, J. J. Tian, Q. Li, L. Y. Chen, J. R, Y. M. Zhao, J. B. Wan, W. H. Ling, and Y. Yang, "Cyanidin-3-O-β-glucoside, a Natural Polyphenol, Exerts Proapoptotic Effects on Activated Platelets and Enhances Megakaryocytic Proplatelet Formation," J Agr Food Chem (2018). Epub ahead of print.（IF=3.412）

2. B. L. Chen, Y. Q. Chen, B. H. Ma, S. F. Yu, L. Y. Li, Q. X. Zeng, Y. T. Zhou, Y. F. Wu, W. L. Liu, J. B. Wan, Y. Yang, and C. W. Li, "Tetrahydrocurcumin, a major metabolite of curcumin, ameliorates allergic airway inflammation by attenuating Th2 responses and suppressing the IL4Ra-Jak1-STAT6 and Jagged1/Jagged2 -Notch1/Notch2 pathways in asthmatic mice," Clin Exp Allergy (2018). Epub ahead of print.（IF=5.158）

3. F. L. Ya, Q. Li, D. L. Wang, S. F. Xie, F. L. Song, R. C. Gallant, Z. Z. Tian, J. B. Wan, W. H. Ling, and Y. Yang, "Cyanidin-3-o-beta-Glucoside Induces Megakaryocyte Apoptosis via PI3K/Akt- and MAPKs-Mediated Inhibition of NF-kappaB Signalling," Thromb Haemost 118 (7), 1215-1229 (2018). (IF=4.952)

4. P. W. Zhang, C. Yang, H. H. Guo, J. B. Wang, S. Q. Lin, H. M. Li, Y. Yang, and W. H. Ling*, "Treatment of coenzyme Q10 for 24 weeks improves lipid and glycemic profile in dyslipidemic individuals," J Clin Lipidol 12 (2), 417-427 e415 (2018). (IF=3.580)

5. Y. L. Yao, Y. Q. Chen, R. Adili, T. McKeown, P. G. Chen, G. H. Zhu, D. Li, W. H. Ling, H. Y. Ni*, and Y. Yang, "Plant-based Food Cyanidin-3-Glucoside Modulates Human Platelet Glycoprotein VI Signaling and Inhibits Platelet Activation and Thrombus Formation," J Nutr 147 (10), 1917-1925 (2017). (IF=4.398)

6. W. Q. Yang, X. Chen, Y. Liu, M. Chen, X. W. Jiang, T. R. Shen, Q. Li, Y. Yang, and W. H. Ling*, "N-3 polyunsaturated fatty acids increase hepatic fibroblast growth factor 21 sensitivity via a PPAR-gamma-beta-klotho pathway," Mol Nutr Food Res 61 (9) (2017). (IF=5.151)

7. W. Q. Yang, X. Chen, M. Chen, Y. P. Li, Q. Li, X. W. Jiang, Y. Yang, and W. H. Ling*, "Fish oil supplementation inhibits endoplasmic reticulum stress and improves insulin resistance: involvement of AMP-activated protein kinase," Food Funct 8 (4), 1481-1493 (2017). (IF=3.289)

8. X. D. Zhang, Y. N. Zhu, F. L. Song, Y. L. Yao, F. L. Ya, D. Li, W. H. Ling, and Y. Yang, "Effects of purified anthocyanin supplementation on platelet chemokines in hypocholesterolemic individuals: a randomized controlled trial," Nutr Metab (Lond) 13, 86 (2016). (IF=3.483)

9. F. L. Song, Y. N. Zhu, Z. Y Shi, J. J Tian, X. J Deng, J. Ren, M. C. Andrews, H. Y. Ni, W. H. Ling, and Y. Yang, "Plant food anthocyanins inhibit platelet granule secretion in hypercholesterolaemia: Involving the signalling pathway of PI3K-Akt," Thromb Haemost 112 (5), 981-991 (2014). (IF=4.952)

10. Z. X. Li, X. R. Li, Y. Zhang, X. Feng, F. Yang, D. F. Su, J. Qiu, W. H. Ling, and Y. Yang, "Erythrocyte membrane fatty acid composition is related to overloaded plasma ferritin in Chinese males with angiographic coronary artery disease," Food & Function 4 (10), 1535-1542 (2013). (IF=3.289)

11. Y. Yang, Z. Y. Shi, A. Reheman, J. W. Jin, C. L. Li, Y. M. Wang, M. C. Andrews, P. G. Chen, G. H. Zhu, W. H. Ling, and H. Y. Ni*, "Plant Food Delphinidin-3-Glucoside Significantly Inhibits Platelet Activation and Thrombosis: Novel Protective Roles against Cardiovascular Diseases," Plos One 7 (5) (2012). (IF=2.766)

12. Y. N. Zhu, W. H. Ling, H. H. Guo, F. L. Song, Q. Y. Ye, T. B. Zou, D. Li, Y. Zhang, G. L. Li, Y. J. Xiao, F. Q. Liu, Z. X. Li, Z. Y. Shi, and Y. Yang, "Anti-inflammatory effect of purified dietary anthocyanin in adults with hypercholesterolemia: A randomized controlled trial," Nutr Metab Cardiovas 23 (9), 843-849 (2013). (IF=3.318)

13. Y. Yang, M. C. Andrews, Y. Hu, D. L. Wang, Y. Qin, Y. N. Zhu, H. Y. Ni, and W. H. Ling, "Anthocyanin Extract from Black Rice Significantly Ameliorates Platelet Hyperactivity and Hypertriglyceridemia in Dyslipidemic Rats Induced by High Fat Diets," J Agr Food Chem 59 (12), 6759-6764 (2011). (IF=3.412)

1.杨燕(7/10), 膳食多酚类活性物质防治代谢性疾病的基础及应用研究, 中华医学会, 科技进步, 二等奖, 2017.1

2.杨燕(7/10), 膳食多酚类活性物质防治代谢性疾病的基础及应用研究, 广东省科学技术奖, 二等奖, 2017.2^[1]

1.徐培林, 葛怡琛, 杨燕, 血小板增进蛋白及其应用, 2008.11, 中国, CN100432102C^[2]

2.Peilin Xu, Yichen Ge, Yan Yang, Platelet promoting protein and the usage thereof, Sep 2011, USA, US 8012927 B2^[3]

1.编委：全国高等学校教材《预防医学》第七版，人民卫生出版社, 2018年

2.编委：全国高等医学数字化规划教材（国家医学电子书包）《预防医学》第一版，军医出版社, 2016年

3.编委：全国高等学校长学制临床专业规划教材《预防医学》第三版，人民卫生出版社, 2015年

4.编委：全国高等学校长学制临床专业规划教材《预防医学学习指导及习题集》第一版，人民卫生出版社，2015年

5.编委：全国高等学校长学制临床专业规划教材《预防医学在线课堂》第三版，人民卫生出版社，2015年

6.编委：全国高等学校教材《卫生学概论》第一版，人民卫生出版社，2012年

7.编委：《肿瘤营养》，第一版，人民卫生出版社，2012年

1. 广东省营养学会第五届理事会 常务理事

2. 广东省营养学会肠道菌群与营养健康专业委员会 副主任委员

3. Molecular Nutrition & Food Research，Journal of Agriculture and Food Chemistry，International Journal of Women’s Health，Central European Journal of Biology等多个国际期刊以及国内学术期刊审稿人