李昂,现任中国科学院上海有机化学研究所研究员。
人物简历
2000.9-2004.6 北京大学化学与分子工程学院,理学学士,导师:杨震教授;
2004.7-2009.11 The Scripps Research Institute,California,USA,Ph.D.,导师:Prof. K. C. Nicolaou;
2010.1-2010.9 Institute of Chemical and Engineering Sciences,Singapore,research fellow,导师:Prof. K. C. Nicolaou;
2010.9-至今中国科学院上海有机化学研究所,“百人计划”研究员
研究方向
复杂的多环及笼状天然产物的全合成;基于分子结构对称性和生物合成路径的高效合成策略的发展;具有重要生理活性的生物碱的合成策略和方法的研究;新颖的生物正交反应(bioorthogonal reaction)及其在化学生物学中的应用。
专家类别
所聘百人;研究员
职务
课题组长
获奖及荣誉
2009年:Eli Lilly Graduate Fellowship;
2008年:国家优秀自费留学生奖学金;
2007–2008年:Bristol-Myers Squibb Graduate Fellowship in Organic Synthesis;
2003年:君政学者,北京大学;
2015年:李昂获得罗氏中国青年研究员奖。[1]
2017年:四面体青年科学家奖(Tetrahedron Young Investigator Award)”[2]
2020年11月14日,获得2020年“科学探索奖”。[3]
代表论著
1.M. Bian, Z. Wang, X. C. Xiong, Y. Sun, C. Matera, K. C. Nicolaou,* and A. Li,* Total Syntheses of Anominine and Tubingensin A, J. Am. Chem. Soc. 2012, 134, Articles ASAP
2.J. Deng, B. Zhu, Z. Lu, H. Yu, A. Li,* Total Synthesis of (–)-Fusarisetin A and Reassignment of the Absolute Configuration of Its Natural Counterpart, J. Am. Chem. Soc
3.C.-C. Tseng, H. Ding, A. Li, Y. Guan, D. Y.-K. Chen, A Modular Synthesis of Salvileucalin B Structural Domains, Org. Lett.
4.K. C. Nicolaou, A. Li, D. J. Edmonds, G. S. Tria, S. P. Ellery, Total Syntheses of Platensimycin and Related Natural Products, J. Am. Chem. Soc
5.K. C. Nicolaou, A. Li, S. P. Ellery, D. J. Edmonds, Rhodium-Catalyzed Asymmetric Enyne Cycloisomerization of Terminal Alkynes and Formal Total Synthesis of (–)-Platensimycin, Angew. Chem. Int. Ed
6.K. C. Nicolaou, A. F. Stepan, T. Lister, A. Li, A. Montero, G. S. Tria, C. I. Turner, Y. Tang, J. Wang, R. M. Denton, D. J. Edmonds, Design, Synthesis and Biological Evaluation of Platensimycin Analogs with Varying Degrees of Molecular Complexity, J. Am. Chem. Soc
7.K. C. Nicolaou, A. Li, Total Syntheses and Structural Revision of α- and β-Diversonolic Esters and Total Syntheses of Diversonol and Blennolide C, Angew. Chem. Int. Ed.
8.K. C. Nicolaou, Y. Tang, J. Wang, A. F. Stepan, A. Li, A. Montero, Total Synthesis and Antibacterial Propoties of Carbaplatensimycin, J. Am. Chem. Soc.
9.K. C. Nicolaou, D. J. Edmonds, A. Li, G. S. Tria, Asymmetric Total Syntheses of Platensimycin, Angew. Chem. Int. Ed.
10.K. C. Nicolaou, A. Li, D. J. Edmonds, Total Synthesis of Platensimycin, Angew. Chem. Int. Ed. 2006, 45, 7086–7090. (This work was highlighted by Nature 2006, 443, 726, Chemical and Engineering News
11.K. C. Nicolaou, R. M. Denton, A. Lenzen, D. J. Edmonds, A. Li, R. M. Milburn, S. T. Harrison, Stereocontrolled Synthesis of Model Core Systems of Lomaiviticins A and B, Angew. Chem. Int. Ed.
12.B. Liang, J. Liu, Y.-X. Gao, K. Wongkhan, D.-X. Shu, Y. Lan, A. Li, A. S. Batsanov, J. A. H. Howard, T. B. Marder, J.-H. Chen, Z. Yang, Synthesis of Thiourea-Oxazolines, a New Class of Chiral S,N-Heterobidentate Ligands: Application in Pd-Catalyzed Asymmetric Bis(methoxycarbonylation) of Terminal Olefins, Organometallics
13.Z. Xiong, N. Wang, M. Dai, A. Li, J. Chen, Z. Yang, Synthesis of Novel Palladacycles and Their Application in Heck and Suzuki Reactions under Aerobic Conditions, Org. Lett.
14.Y. Zhang, A. Li, Z. Yan, G. Xu, C. Liao, C. Yan, (ZrO2)0.85(REO1.5)0.15 (RE = Sc, Y) solid solutions prepared via three Pechini-type gel routes: 1. gel formation and calcination behaviors, Journal of Solid State Chemistry
15.Y. Zhang, A. Li, Z. Yan, G. Xu, C. Liao, C. Yan, (ZrO2)0.85(REO1.5)0.15 (RE=Sc, Y) solid solutions prepared via three Pechini-type gel routes: 2-sintering and electrical properties, Journal of Solid State Chemistry
16.Y. Zhang, A. Li, Z. Yan, C. Liao, C. Yan, Calcination Time Effects on the Particle Size , Specific Surface Area and Morphology of Rare Earth Oxides (III), Journal of the Chinese Rare Earth Society (Chinese Edition)
17.Y. Zhang, Z. Yan, A. Li, X, Jiang, L. Gu, C. Liao, C. Yan, Effects of Precipitation Conditions on Specific Surface Area and Morphology of Rare Earth Oxides(II), Journal of the Chinese Rare Earth Society (Chinese Edition)[4]
已指导学生
王震0219132李波0263220鲁照永0119132陈浩0119132邓军0119132郦勇0119132孟占朝0119132孙域0119132陆钊洪0119132
参考文献:[5]
现指导学生
李海龙0119132张翔0219132郭瑞0219132杨鹏0119132李健0119132周述鹏0119132张纹豪0119132郭志聪0219132吕铭0219132张飞0119132吴頔珉0119132叶文博0119132
参考文献:[5]
参考资料 5
- 李昂 — 中国科学院上海有机化学研究所
- 两名中国学者获四面体青年科学家奖 — news.sciencenet.cn
- 50位青年学者获2020年“科学探索奖” 其中7位为河南籍学者- — 大河网
- 李昂 — 中国科学院上海有机化学研究所
- 李昂 — 中国科学院大学