氢原子百科 
李忠，男，博士，出生于1968年7月。现任华东理工大学药学院教授，博士生导师，华东理工大学药物化工研究所所长。
李忠教授主要从事绿色化学农药分子设计及合成的研究，并在顺式硝基烯类新烟碱杀虫剂创制研究方面取得突破性进展，发现了三类具有全新结构的超高活性化合物，活性显著超越目前最著名的杀虫剂品种吡虫啉，并对抗性品系超高效。申请国际PCT发明专利3项，中国发明专利7项（2项已获授权），相关专利化合物的国内实施许可权已经以2000万人民币的价格转让给江苏克胜集团。[1]
人物经历
教育经历
1993年，获华东理工大学物理化学专业理学硕士学位；
1996年，获华东理工大学精细化工专业工学博士学位；[1]
工作经历
1995-2004年，华东理工大学，副教授；教授，博士生导师；
1999-2001年，获得日本国立AIST和ITIT博士后基金资助，在日本工业技术研究院从事博士后研究；
2001年至今，华东理工大学药学院教授，华东理工大学药物化工研究所所长。[1]
研究方向
1）昆虫行为调控剂的分子设计、合成及作用机制研究
主要包含：昆虫生长调节剂、昆虫飞行调控剂、新烟碱杀虫剂等绿色农药的创制研究；
2）含硒化合物的设计合成及生物性能研究
主要包含：含硒除草剂、含硒植物生长调节剂的创制及生物性能研究[1]
代表论著
Yanli Wang, Jiagao Cheng, Xuhong Qian*, Zhong Li*. “Actions between neonicotinoids and key residues of insect nAChR based on an ab initio quantum chemistry study: Hydrogen bonding and cooperative π—π interaction”. Bioorgan. Med.Chem. 2007, 15, 2624-2630.Feng Fan, Zhong Li*, Xiaoyong Xu, Xuhong Qian*. “Quantitative Aggregation- Activity Relationship (QAAR): Supermolecular view, dimer as the simplest aggregation state and monomolecule.” QSAR & Combinatorial Science, 2007, 26, 737-743.Zhongzhen Tian, Zhaoxing Jiang, Zhong Li*, Gonghua Song*, Qingchun. Huang. “Syntheses and Biological Activities of octahydro-1H-cyclopenta[d] pyrimidine derivatives”. J. Agric. Food Chem., 2007, 55, 143-147.ZhongzhenTian, Xusheng Shao, Zhong Li*, Xuhong Qian*, Qingchun Huang, “Synthesis, Insecticidal Activity, and QSAR of Novel Nitromethylene Neonicotinoids with Tetrahydropyridine Fixed cis Configuration and Exo-Ring Ether Modification”, J. Agric. Food Chem., 2007, 55, 2288-2292.Xiaobao Yang, Li Zhu,Yuedong Zhou, Zhong Li*, Hongbin Zhai*, “Efficient Synthesis of Monosubstituted 3-Alkynylfurans via Suzuki Coupling”, Synthesis, 2008, (No.11), 1729–1732.Xiaobao Yang, Bin Cheng, Zhong Li*, Hongbin Zhai*, “Formal Asymmetric Synthesis of (–)-Aphanorphine via Ring- Closing Metathesis Reaction”, SYNLETT, 2008, (No.18), 2821-2822.Shaoyong Ke, Zhong Li, Xuhong Qian*, “1,3,4-Oxadiazole-3(2H)- carboxamide derivatives as potential novel class of monoamine oxidase (MAO) inhibitors: Synthesis, evaluation, and role of urea moiety”. Bioorg. Med. Chem., 2008, 16, 7565–7572.Chuanxiang Liu, Xuhong Qian,* Guangqiang Sun, Liwei Zhao and Zhong Li*, Chromogenic and fluorescent chemodosimeter for fluoride ion based on novel anion-catalyzed intramolecular hydrogen transfer, New J. Chem., 2008, 32, 472-476.Chuanxiang Liu, Xuhong Qian*, Jiaobing Wang, Zhong Li*, Anion recognition by a novel Fipronil-based receptor: efficient deprotonation or stable intermolecular hydrogen bonding, Tetrahedron Lett., 2008, 49, 1087-1090.Ming-Yi Cai, Zhong Li*, Qingchun Huang, and Gonghua Song* “{[1-(Arylmethyl) piperidin-4-yl]oxy} -(trifluoromethyl)- pyridines: Ketanserin Analogues with Insect Growth Regulating Activity” Chem. Biodivers, 2008, 1844-1855.Xusheng Shao, Wenwen Zhang, Yanqing Peng, Zhong Li*, Zhongzhen Tian, Xuhong Qian *, “cis-Nitromethylene neonicotinoids as new nicotinic family: Synthesis, structural diversity, and insecticidal evaluation of hexahydroimidazo[1,2-a]pyridine”, Bioorg. Med. Chem. Lett., 2008, 18, 6513-6516.Xiaobao Yang, Hongbin Zhai,* Zhong Li*, “Enantiocontrolled Synthesis of (-)-9-epi- Pentazocine and (-)-Aphanorphine”. Org. Lett., 2008, 10 , 2457–2460.Feng Fan, Jiagao Cheng, Zhong Li*, Xiaoyong Xu, Xuhong Qian*. “Novel dimer based descriptors with solvational computation for QSAR study of oxadiazoylbenzoyl-ureas as novel isect-growth regulators”. Journal of Computational Chemistry. 2009, published online, DOI: 10.1002/jcc.2135.Feng Fan, Zhiqi You, Zhong Li*, Jiagao Cheng, Yun Tang, Zhenhua Tang. “A Butterfly Effect: Highly Insecticidal Resistance Caused by Only a Conservative Residue Mutated of Drosophila Melanogaster Acetylcholinesterase”. Journal of Molecular Modeling, 2009, 15, 1229-1236.Xusheng Shao, Zhong Li*, Xuhong Qian, Xiaoyong Xu*. “Design, Synthesis, and Insecticidal Activities of Novel Analogues of Neonicotinoids: Replacement of Nitromethylene with Nitroconjugated System”. J. Agric. Food Chem. 2009, 57, 951–957.[1]
获奖情况
参考资料 1
- 李忠 — 华东理工大学药学院