白春学

白春学，复旦大学附属中山医院教授，上海市呼吸病研究所所长，兼任中国肺癌防治联盟主席。^[1]

1997年2月－1998年11月在美国加州大学旧金山分校做博士后研究

1986年－1989年就读于原上海医科大学研究生院，获博士学位

1985年5月－1985年10月在WHO/日本进修结核防治

1979年－1982年就读于北京中国协和医科大学研究生院，获硕士学位

1972年－1975年就读于哈尔滨医科大学医疗系 

1989年，复旦大学附属中山医院

（1）Qunying Hong, Guoming Wu, Guisheng Qian, Chengping Hu，Jianying Zhou，Liangan Chen，Weimin Li，Jing Li，Xin Gong，Chunxue Bai. Prevention and managementof Lung Cancer in China. Cancer.2015,121:3080-3088(IF=5.649)

（2）Jing Li, Jian Zhou, Dan Zhang, Yuanlin Song, Jun She, and Chunxue Bai. Bone marrow-derived mesenchymal stem cells enhance autophagy via PI3K/AKT signalling to reduce the severity of ischemia/reperfusion-induced lung injury. Journal of Cellular and Molecular Medicine. 2015.19(10):2341-2351. (IF=4.014)

（3）Niels H Chavannes1, Robert S Du Puy1 and Chunxue Bai. Suggestions for health information technology trials for respiratory disorders in low- and middle-income country settings: what can we learn from trials in high-income country settings? npj Primary Care Respiratory Medicine (2015) 25, 15045; doi:10.1038/npjpcrm.2015.45 （IF=1.447）

（4）Tang X, Bi J, Yang D, Chen S, Li Z, Chen C, Wang G, Ju M, Wang J, Wang Y, Gong R, Bai C, Zhou H, Jin X, Song Y. Emphysema is an independent risk factor for 5-year mortality in patients with bronchiectasis. Clin Respir J. 2015 (IF=2.147)

（5）Chunxue Bai, Chang-Min CHOI, Chung Ming CHU, Devanand ANANTHAM,James HO, Ali Zamir KHAN, Jang-Ming LEE, Shi Yue LI, Sawang SAENGHIRUNVATTANA, Anthony YIM. Evaluation of pulmonary nodules: clinical practice consensus guidelines for Asia. CHEST 2016; 150(4):877-893 (IF=6.136)

（6）Jie Liu, Zheng Li, Zilong Liu, Fen Zhu, Wenjing Li, Hong Jiang, Xiaodan Wu,Yuanlin Song, Shanqun Li, Chunxue Bai. Exhaled nitric oxide from the central airway and alveoli in OSAHS patients: the potential correlations and clinical Implications. Sleep Breath. 2016，20:145–154 (IF=2.482)

（7）Haiyan Ge, Huili Zhu, Nuo Xu, Dan Zhang, Jiaxian Ou, Guifang Wang, Xiaocong Fang, Jian Zhou, Yuanlin Song, Chunxue Bai. Increased lung ischemia-reperfusion injury in aquaporin 1 null mice is mediated via decreased HIF-2α stability. Am J Resp Cell Mol. 2016, 54(6):882-891. (IF:4.082)

（8）Lin Tong, Jian Zhou, Linyi Rong, Eric J. Seeley, Jue Pan1, Xiaodan Zhu, Jie Liu, Qin Wang, Xinjun Tang, Jieming Qu, Chunxue Bai & Yuanlin Song. Fibroblast Growth Factor-10 (FGF-10) Mobilizes Lung-resident Mesenchymal Stem Cells and Protects Against Acute Lung Injury. Scientific RepoRts, 2016, 6:21642. DOI: 10.1038/srep21642 (IF= 5.228)

（9）Dan Zhang, Chichi Li, Jian Zhou, Yuanlin Song, Xiaocong Fang, Jiaxian Ou, Jing Li, and Chunxue Bai. Autophagy protects against ischemia/reperfusion- induced lung injury through alleviating blood–air barrier damage. J Heart Lung Transplant 2015;34:746–755 (IF= 7.509).

（10）Hai-Xing Zhu, Jie-Bai Zhou Xiao-Dan Zhu, Jian Zhou, Jing Li, Yuan-Lin Song, Chunxue Bai. Impaired self-healing capacity in airway epithelia lacking aquaporin-3. Respiratory Physiology & Neurobiology. 2016, 233:66-72. (IF=1.773)

（11）Nanshan Zhong, Hwa S. Moon, Kwan H. Lee, Aziah A. Mahayiddin,Watchara Boonsawat, Marie G.D. Isidro, Chunxue Bai, Achim Mueller,Norbert Metzdorf, Antonio Anzueto. TIOtropium Safety and Performance In Respimat (TIOSPIR): Analysis of Asian cohort of COPD patients. Respirology, July 2016, 21(8):1397-1403. (IF=3.078)

（12）Feng N, Wang Q, Zhou J, Li J, Wen X, Chen S, Zhu Z, Bai C, Song Y, Li H. Keratinocyte growth factor-2 inhibits bacterial infection with Pseudomonas aeruginosa pneumonia in a mouse model. J Infect Chemother. 2016, 22(1):44-52. (IF=1.452)

（13）Zhang Ziqiang, Zhou Nanjiang, Huang Jianguo, Ho Tsui-Ting, Zhu Zhuxian, Qiu Zhongmin, Zhou Xinchun, Bai Chunxue, Wu Fangting, Xu Min, Mo Yin-Yuan. Regulation of androgen receptor splice variant AR3 by PCGEM1. Oncotarget. 2016, 7(13):15481-15491. (IF=5.008)

（14）Wenxue Chen, Shaohua Lu, Jiaxian Ou, Guifang Wang, Yukun Zu, Fener Chen, Chunxue Bai. Metabonomic characteristics and biomarker research of human lung cancer tissues by HR1H NMR spectroscopy. Cancer Biomarkers. 2016, 16(4): 653-664. (IF=1.736)

（15）Chen C, Wang M, Zhu Z, Ou J, Xi X, Tang X, Lao X, Seeley E, Li T, Fan X, Du C, Wang Q, Yang L, Hu Y, Bai C, Zhang Z, Lu S, Song Y, Zhou W. Multiple gene mutations indentified in patients infected with influenza A (H7N9) virus. Sci Rep. 2016, 6:25614. (IF=5.228)

（16）Cook-Mills J, Gebretsadik T, Abdala-Valencia H, Green J, Larkin EK, Dupont WD, Shu XO, Gross M, Bai Chunxue, Gao YT, Hartman TJ, Rosas-Salazar C, Hartert T. Interaction of vitamin E isoforms on asthma and allergic airway disease. Thorax. 2016, 71(10):954-956. (IF=8.121)

（17）Yi Jia, Xu Fang, Xuehua Zhu, Chunxue Bai, Lei Zhu, Meiling Jin, Xiangdong Wang, Min Hu, Renhong Tang, Zhihong Chen. IL-13(+) Type 2 Innate Lymphoid Cells Correlate with Asthma Control Status and Treatment Response. American Journal of Respiratory Cell and Molecular Biology. 2016, 55(5):675-683. (IF=4.082)

（18）Gang Wang, Luyang Cao, Xiaowen Liu, Nathan A Sieracki, Anke Di, Xi Wen, Yong Chen, Shalina Taylor, Xiaojia Huang, Chinnaswamy Tiruppathi, You-Yang Zhao, Yuanlin Song, Xiaopei Gao, Tian Jin, Chunxue Bai, Asrar B Malik, Jingsong Xu. Oxidant Sensing by TRPM2 Inhibits Neutrophil Migration and Mitigates Inflammation. Developmental Cell. 2016, 38(5): 453-462. (IF=9.338)

（19）Dongni Hou, Tianlei Ying, Lili Wang, Cuicui Chen, Shuihua Lu, Qin Wang, Eric Seeley, Jianqing Xu, Xiuhong Xi, Tao Li, Jie Liu, Xinjun Tang, Zhiyong Zhang, Jian Zhou, Chunxue Bai, Chunlin Wang, Miranda Byrne-Steele, Jieming Qu, Jian Han, Yuanlin Song. Immune Repertoire Diversity Correlated with Mortality in Avian Influenza A (H7N9) Virus Infected Patients. Scientific Reports. 2016, 6:33843. (IF=5.228)

（20）Wenxue Chen, Shaohua Lu, Guifang Wang, Fener Chen, Chunxue Bai. Staging research of human lung cancer tissues by high-resolution magic angle spinning proton nuclear magnetic resonance spectroscopy (HRMAS(1)H NMR) and multivariate data analysis. Asia-Pacific Journal of Clinical Oncology. 2016. (IF=1.722)

（21）Shiming Wang, Xiao Song, Xiaoying Li, Xueying Zhao, Hongyan Chen, Jiucun Wang, Junjie Wu, Zhiqiang Gao, Ji Qian, Baohui Han, Chunxue Bai, Qiang Li & Daru Lu. RICTOR polymorphisms affect efficiency of platinum-based chemotherapy in Chinese non-small-cell lung cancer patients. Pharmacogenomics. 2016, 17(15):1637-1647. (IF=2.71)

（22）Dong Yang, Meiling Jin, Chunxue Bai, Jian Zhou, Yao Shen. Peroxiredoxin 6 suppresses Muc5ac overproduction in LPS-induced airway inflammation through H2O2-EGFR-MAPK signaling pathway. Respiratory Physiology & Neurobiology. 2017, 236:84-90. (IF=1.773)

（23）Yuanlin Song, Linlin Wang, Jian Wang, Chunxue Bai. Aquaporins in Respiratory System. Advances in Experimental Medicine and Biology. 2017, 969:115-122. (IF=1.953)

（24）Shujing Chen, Yutong Gu, Liping Qiao, Cuicui Wang, Yuanlin Song, Chunxue Bai, Yuchun Sun, Haiying Ji, Min Zhou, Hongli Wang, Renjie Chen, Haidong Kan. Fine particular constituents and lung dysfunction: A time-series panel study. Environmental Science & Technology. 2017, 51(3):1687-1694. (IF=5.393)

（25）Shujing Chen Changhui Wang Bing li guochao shi huiping li Jing Zhang Yutong gu Jian Zhou Yuanlin song Chunxue Bai.risk factors for FeV1 decline in mild COPD and high-risk populations. International Journal of COPD 2017:12 435–442 (IF= 3.046)

（26）Lian Wu, Jing Zhang, Jie Ming Qu, Chunxue Bai, Mervyn J Merrilees. Deposition of insoluble elastin by pulmonary fibroblasts from patients with COPD is increased by treatment with versican siRNA，International Journal of Chronic Obstructive Pulmonary Disease, 2017, 12:267—273, DOI https://doi.org/ 10.2147/COPD.S116217(IF= 3.046)

（27）Xixin Yan, Yuanlin Song,, Ce Shen wenbing Xu, Liangan Chen, Jian Zhang, Huiguo Liu, Mao Huang Guoxiang Lai, Guishen Qian, Jing wang, Xianwei Ye, Jinping Zheng, Chunxue Bai. Mucoactive and antioxidant medicines for COPD: consensus of a group of Chinese pulmonary physicians. International Journal of COPD 2017:12 803–812. (IF= 3.046)

（28）Dan Zhang, Chichi Li, Yuanlin Song, Jian Zhou, Yuping Li, Jing Li, Chunxue Bai. Integrin αvβ5 inhibition protects against ischemia/reperfusion-induced lung injury in an autophagy-dependent manner. Am J Physiol Lung Cell Mol Physiol. 2017, 313: 384-394. (IF=4.01)

（29）Yumin Zhou, Nan-shan Zhong, Xiaochen Li, Shuyun Chen, Jinping Zheng., Dongxing Zhao, Weimin Yao , Rongchang Zhi, Liping Wei, Bingwen He, Xiangyan Zhang, Changli Yang, Ying Li, Fenglei Li, Juan Du, Jianping Gui, Bin Hu, Chunxue Bai, Ping Huang, Gang Chen, Yongjian Xu, Changzheng Wang, Biao Liang, Yinhuan Li, Guoping Hu, Hui Tan, Xianwei Ye, Xitao Ma, Yan Chen, Xiwei Hu, Jia Tian, Xiaodan Zhu, Zhe Shi, Xiufang Du, Minjing Li, Shengming Liu, Ronghuan Yu, Jianping Zhao, Qianli Ma, Canmao Xie, Xiongbin Li, Tao Chen, Yingxiang Lin, Lizhen Zeng, Changxiu Ye, Weishu Ye, Xiangwen Luo, Lingshan Zeng, Shuqing Yu, Wei-jie Guan, and Pixin Ran. Tiotropium in Early-Stage Chronic Obstructive Pulmonary Disease. N Engl J Med 2017; 377:923-935. (IF= 72.406)

（30）Chunxue Bai, Masakazu Ichinose, Sang Haak Lee, Kwan Ho Lee, Olaf Jöns, Ulrich Bothner, Yihua Zhao, Roland Buhl. Lung function and long-term safety of tiotropium + olodaterol in East Asian patients with COPD. International Journal of COPD 2017: 12:3329–3339. (IF= 3.046)

（31）Vanbang Le, Dawei Yang, Yu Zhu, Bingbing Zheng, Chunxue Bai, Quocthinh Nguyen, and Hongcheng Shi. Automated Classification of Pulmonary Nodules for Lung Adenocarcinomas Risk Evaluation: An Effective CT Analysis by Clustering Density Distribution Algorithm. J. Med. Imaging Health Inf. 2017, 7(8):1753-1758 (IF= 0.621).

（32）Chen Wang, Jianying Xu, Lan Yang, Yongjian Xu, Xiangyan Zhang， Chunxue Bai， Jian Kang， Pixin Ran， Huahao Shen， Fuqiang Wen，Kewu Huang， Wanzhen Yao， Tieying Sun， Guangliang Shan， Ting Yang, Yingxiang Lin， Sinan Wu， Jianguo Zhu， Ruiying Wang,Zhihong Shi, Jianping Zhao, Xianwei Ye, Yuanlin Song, Qiuyue Wang, Yumin Zhou, Liren Ding, Ting Yang§, Yahong Chen, Yanfei Guo, Fei Xiao,Yong Lu, Xiaoxia Peng, Biao Zhang, Dan Xiao, Chung-Shiuan Chen, Zuomin Wang, Hong Zhang, Xiaoning Bu, Xiaolei Zhang, Li An, Shu Zhang,Zhixin Cao, Qingyuan Zhan, Yuanhua Yang, Bin Cao, Huaping Dai, Lirong Liang, Jiang He†, for the China Pulmonary Health Study Group.Prevalence and risk factors of chronic obstructive pulmonary disease in China (the China Pulmonary Health [CPH] study):a national cross-sectional study. The Lancet. 2018, 391(10131): 1706-1717. (IF=47.83)

（33）Chen Bao, Xiaocen Wang, Yuan Ji, Chen Xu, Dong Yang, Chunxue Bai. Clinical and pathological characteristics of pulmonary mucosa-associated lymphoid tissue lymphoma: a case report. Int J Clin Exp Med. 2017, 10(4): 7231-7235. (IF=1.17)

（34）Jian Wang, Jianan Huang, Linlin Wang, CuiCui Chen, Dong Yang, Meiling Jin, Chunxue Bai, Yuanlin Song. Urban particulate matter triggers lung inflammation via the ROS-MAPK-NF-kB signaling pathway. J Thorac Dis 2017, 9(11): 4398-4412. (IF=2.365)

（35）Fanglei Liu, Chunxue Bai, Zhongliang Guo. The prognostic value of osteopontin in limited-stage small cell lung cancer patients and its mechanism. Oncotarget, 2017, 8(41): 70084-70096. (IF=4.73)

（36）Haixing Zhu, Lin Shi, Yong Zhang, Yichun Zhu, Chunxue Bai, Xiangdong Wang, Jiebai Zhou. Myocyte enhancer factor 2D provides a cross‑talk between chronic inflammation and lung cancer. Journal of translational medicine. 2017, 15:65-74. (IF=3.93)

（37）Xun Wang, Xiaojing An, Xiaocen Wang, Chen Bao, Jing Li, Dong Yang, Chunxue Bai. Curcumin ameliorated ventilator-induced lung injury in rats. Biomedicine & Pharmacotherapy. 2018, 98: 754-761. (IF=2.42)

（38）Chunxue Bai. Letter from China. Respirology 2018，23：718– 719 . (IF=3.256)

（39）NUO XU, XUEHUA CHEN, SHENGDI WU, MAOSONG YE, MEILING ZHANG, LIN TONG, XIAODAN ZHU, JIE LIU, FEIFEI HU and Chunxue Bai. Chronic pulmonary complications associated with toxic epidermal necrolysis: A case report and literature review. EXPERIMENTAL AND THERAPEUTIC MEDICINE 2018,16: 2027-2031(IF=1.41)

（40）GE ZHANG, TAO FANG2, MEIJIA CHANG1, JING LI, QUNYING HONG, Chunxue Bai, and JIAN ZHOU. Calpain 2 knockdown promotes cell apoptosis and restores gefitinib sensitivity through epidermal growth factor receptor/protein kinase B/survivin signaling. ONCOLOGY REPORTS 2018: 1937-1946. (IF= 2.976)

（41）Shaohua Lu, Hui Kong, Yingyong Hou, Di Ge, Wei Huang, Jiaxian Ou, Dawei Yang, Li Zhang, Guoming Wu, Yong Song, Xiaoju Zhang, Changwen Zhai, Qun Wang, Hongguang Zhu, Ying Wu, Chunxue Bai. Two plasma microRNA panels for diagnosis and subtype discrimination of lung cancer. Luan cancer. 2018, 123, 44-51. (IF=4.468)

（42）Jian Zhou, Meijia Chang, Jing Li, Tao Fang, Jie Hu, Chunxue Bai. Knockdown of annexin A5 restores gefitinib sensitivity by promoting G2/M cell cycle arrest. Respiratory research. 2018, 19:96. (IF=3.841)

（43）Meijia Chang, Jie Hu, Tao Fang, Jing Li, Yuanlin Song, Jian Zhou, Chunxue Bai. PLIN2 confers gefitinib resistance by inhibiting cell apoptosis via activation of EGFR/AKT/survivin in PC9R cells. ONCOTARGET. 2018. （IF=4.65）

（44）Jian Zhou, KL Kwak, Z Wu, D Yang, J Li, M Chang, Y Song, H Zeng, LJ Lee, J Hu, C Bai. PLAUR Confers Resistance to Gefitinib Through EGFR/P-AKT/Survivin Signaling Pathway. Cell Physiol Biochem. 2018,47(5):1909-1924. (IF= 4.83)

（45）Dawei Yang, Xiaoju Zhang, Charles A. Powell, Jun Ni, Bin Wang, Jianya Zhang, Yafei Zhang, Lijie Wang, Zhihong Xu, Li Zhang, Guoming Wu, Yong Song, Wenhua Tian, Jia-an Hu, Yong Zhang, Jie Hu, Qunying Hong, Yuanlin Song, Jian Zhou, and Chunxue Bai. Probability of Cancer in High-Risk Patients Predicted by the Protein-Based Lung Cancer Biomarker Panel in China: LCBP Study. Cancer 2018;124:262-70(IF= 6.072).

（46）Jun Yin, Chunxue Bai. Pharmacotherapy for Adult Patients with Acute Respiratory Distress Syndrome. Chinese Medical Journal, 2018, 131(10):1138-1041(IF=1.064).

（47）Linlin Wang, Meng Shi, Lin Tong, Jian Wang, Shimeng Ji, Jing Bi, Cuicui Chen, Jinjun Jiang, Chunxue Bai, Jian Zhou, and Yuanlin Song. Lung-Resident Mesenchymal Stem Cells Promote Repair of LPS-Induced Acute Lung Injury via Regulating the Balance of Regulatory T cells and Th17 cells. Inflammation. 2019. 42(1):199-210. (IF=2.92)

（48）Jian Zhou; Guimei Qu; Ge Zhang; Zuoren Wu; Jing Liu; Dawei Yang; Jing Li; Meijia Chang; Hengshan Zeng; Jie Hu; Tao Fang; Yuanlin Song; Chunxue Bai. Glycerol kinase 5 confers gefitinib resistance through SREBP1/SCD1 signaling pathway.Journal of Experimental & Clinical Cancer Research. 2019, (IF= 6.217).

（49）Wang B.Q., Shi M., Zhang J.P., Wu X., Chang M.J., Chen Z.H., Shen H.H., Song Y.L., Zhou J, Bai C.X. (2018a) Knockdown of Tfpi-Anchored Endothelial Cells Exacerbates Lipopolysaccharide-Induced Acute Lung Injury via NF-κB Signaling Pathway. Shock. 2019 ;51(2):235-246. (IF=2.75)

（50）Yuanlin Song, Chunxue Bai. XueBiJing Injection versus Placebo for Critically Ill Patients with Severe Community-Acquired Pneumonia: A Randomized Controlled Trial，Critical Care Medicine, 2019，Volume 47 - Issue 9 - p e735-e743v(IF=6.63)

（1）Michael A. Matthay, Collen Horan, Chunxue Bai, and Yibing Wang. Alceolar epithelialfluid transport under normal pathological conditions. P71-85, in acute respiratory distress syndrome, Edited by Matalon and Sznajder, Plenum Press, New York, 1998

（2）Christoph Thuemmler and Chunxue Bai Editor-in-chief: e-Health 4.0:How Virtualization and Big Data are Revolutionizing Healthcare，Springer，2016

（3）Yuanlin Song, Linlin Wang, Jian Wang, and Chunxue Bai， Aquaporins in Respiratory System. P115-123, in Aqaporins, Edited by Baoxue Yang, Springer，2017.

（4）白春学 李为民 陈良安. 主编 《早期肺癌》. 人民卫生出版社,北京 2018（80万字）

（5）白春学,宋元林,胡成平.主编:上海交通大学出版社“精准医学出版工程·精准医学基础系列”图书呼吸系统疾病的精准预防、诊断与治疗,上海 （90万字）待出版

（6）白春学 赵建龙. 主编 《物联网医学》. 科学出版社,北京 2016（73万字）