楼慧强

楼慧强

楼慧强

楼慧强,男,博士,2009年成为中国农业大学特聘教授,同年入选教育部“新世纪优秀人才和创新团队”,现任微生物学与免疫学系教授、博士生导师。主要以真核微生物酿酒酵母( Saccharomyces cerevisiae )为模式系统,在基因和蛋白相互作用网络水平探求基因组不稳定性的分子机理,及其与疾病/癌症发生的关系。目前致力于相互作用组学技术构建DNA复制期(即S期)的蛋白质调控网络。代表性论文包括Mol Cell封面文章等。

楼慧强,男,博士,2009年成为中国农业大学特聘教授,同年入选教育部“新世纪优秀人才和创新团队”,现任微生物学与免疫学系教授、博士生导师。

教师简介

主要以真核微生物酿酒酵母( Saccharomyces cerevisiae )为模式系统,在基因和蛋白相互作用网络水平探求基因组不稳定性的分子机理,及其与疾病/癌症发生的关系。目前致力于相互作用组学技术构建DNA复制期(即S期)的蛋白质调控网络。代表性论文包括Mol Cell封面文章等。

学习与工作经历

2009.3- Professor, Department of Microbiology and Immunology,

College of Biological Sciences, China Agricultural University.

2006.8-2009.3 CIRM Senior Research Fellow,

Divisions of Chemistry and Biology, California Institute of Technology, USA.

2004.8-2006.8 Postdoctoral Scholar,

Division of Chemistry and Chemical Engineering, California Institute of Technology, USA.

1997.9-2004.2 Doctor of Philosophy,

Institute of Microbiology, Chinese Academy of Sciences, China.

1992.9-1997.7 Bachelor of Science,

Department of Cell Biology and Genetics, Peking University, China.

研究方向

In budding yeast:

Genome instability, Diseases and Cancer.

DNA replication and the S phase checkpoint.

DNA damage and replication stress signaling pathways.

Asymmetric segregation and cell aging.

In herperthermophilic archaea:

Genome stability under boiling growth temperature.

Epigenetic adaptation to the extremely harsh environment

主讲课程

研究生课程

《Progress in Microbiology》

《Advanced Progress in Microbiology》

《文献研读》

发表文章

Huiqiang Lou, Makiko Komata, Yuki Katou, Zhiyun Guan, Clara C. Reis, Martin Budd, Katsuhiko Shirahige, and Judith L. Campbell*. Mrc1 and DNA polymerase ε function together in linking DNA replication and the S phase checkpoint. Mol. Cell 2008, 32(1):106-117. (On the cover).

[Previews] Labib Karim, Making Connections at DNA Replication Forks: Mrc1 Takes the Lead. Mol. Cell, 2008, 32(2):166-168.

Huiqiang Lou, Zhenhong Duan, Tong Sun, and Li Huang*. Cleavage of double-stranded DNA by the intrinsic 3’-5’ exonuclease activity of DNA polymerase B1 from the hyperthermophilic archaeon Sulfolobus solfataricus at high temperature. FEMS Microbiol. Lett. 2004, 231: 111-117.

Huiqiang Lou, Zhenhong Duan, Xiaofeng Huo, and Li Huang*. Modulation of hyperthermophilic DNA polymerase activity by archaeal chromatin proteins. J Biol. Chem. 2004, 279(1):127-32.

Likui Zhang, Huiqiang Lou, et. al. Extremophile. Published online: 11 December 2009

获得荣誉

指导研究生获得校长奖学金1人、国家奖学金6人、参加CSHL或Gordon 国际大会10余人次;指导研究生和本科生获得北京市优秀毕业生、北京市优秀毕业论文若干人次;指导本科生国际iGEM获得银奖,在全国和北京市各类创新项目和竞赛也屡获佳绩。[1]

参考资料 1

  1. 中国农业大学生物学院 教授 楼慧强 — 中国农业大学
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