刘雳宇

刘雳宇，男，1980年出生，中国科学院物理研究所百人计划特聘研究员，重庆大学物理学院教授，博士生导师。他在癌症生物物理、微流控类器官芯片和自组织机器人集群等领域有着深入的研究。刘雳宇是国家级青年人才、国家“973”青年项目首席科学家、国家级人才联谊会副秘书长、重庆市青年领军人才协会副理事长、重庆市欧美同学会副会长、重庆市政协常委。^[1]

刘雳宇1980年生于成都。2004年毕业于中国科学技术大学力学与机械工程系，获得学士学位；2008年获得香港科技大学纳米科学与纳米技术博士学位。2012年加入中国科学院物理研究所“百人计划”，担任特聘研究员和博士生导师。2015年，他加入重庆大学物理学院，担任教授，并曾任物理学院常务副院长。刘雳宇还担任政协重庆市第六届常务委员。^[1]

刘雳宇的研究方向包括癌症生物物理，专注于探索基于改变肿瘤微环境的癌症治疗新方法；微流控类器官芯片的研究与应用；以及自组织机器人集群，研究自组织集群行为涌现的机理。^[1]

刘雳宇团队在国际上首次发现取向性的人体微环境能够极大增强癌细胞转移时侵袭血管的能力，首次实验观测到了癌细胞侵袭的博弈行为等，这些研究在国际学术圈产生了重要影响。^[1]

刘雳宇获得的荣誉包括中国科学院“卢嘉锡”人才奖、东京工业大学青年科学家奖、重庆市十佳科技青年奖、重庆市物理学科带头人等。^[1]

1. 科技部“973计划”青年科学家专题（2013CB837200）

“三维微纳米生物芯片在肝癌和大肠癌肝转移中的分子机理研究及其临床应用”

2. 自然科学基金面上项目(11604030)

“功能性弹性血管的动力学及在重大疾病研究中的应用”

3. 自然科学基金面上项目(11474345)

“3-D生物芯片中癌细胞侵袭组织的集体行为和动力学研究“

4. 北京市自然科学基金（7154221）

“数字影像分析结合3-D打印技术探索心血管FFR的体外无创诊断”

5. 自然科学基金面上项目（11974066）

“介观尺度下癌细胞侵袭取向性胶原纤维的动力学研究” ^[1]

1. "The Impact of Hybrid Compositional Film/Structure on Organic-Inorganic Perovskite Solar Cells", Y. Wu, W. Chen, G. Chen,L. Liu, Z. He, R. Liu,Nanomaterials8 (6) doi: 10.3390/nano8060356 (2018)

2. "Realizations of highly heterogeneous collagen networks via stochastic reconstruction for micromechanical analysis of tumor cell invasion", H. Nan, L. Liang, G. Chen,L. Liu, R. Liu, Y. Jiao,Physical Review E97 (3) 033311 (2018)

3. "Microfabrication-Based Three-Dimensional (3-D) Extracellular Matrix Microenvironments for Cancer and Other Diseases", K. Song, Z. Wang, R. Liu, G. Chen,L. Liu, InternationalJournal of Molecular Science19 (4) doi:10.3390/ijms19040935 (2018)

4. "SKPM study on organic-inorganic perovskite materials", K. Song, Y. Wu, X. Chen, Y. He,L. Liu, G. Chen, R. Liu,AIP Advances8 (3) 0351114 (2018)

5. Y. Liu, X. Zhang, Y. Wu, W. Liu, X. Li, R. Liu,L. Liu, J. Shuai, "Derivation of persistent time for anisotropic migration of cells",Chin. Phys. BVol. 26, No. 12 (2017) 128707 (2017)

6. Q. Fan, R. Liu, Y. Jiao, C. Tian, James D. Farrell, X. Wang, F. Zhang, W. Yuan, H. Han, J. Chen, Y Yang, X. Zhang, F. Ye, M. Li, Z. Ouyang, andL. Liu, "A novel 3-D bio-microfluidic system mimicking in vivo heterogeneous tumour microstructure reveals complex tumourstroma interactions",Lab on a ChipDOI:10.1039/C7LC00191F(2017)

7. W. Han, S. Chen, W.Yuan, Q. Fan, J. Tian, X. Wang, L. Chen, X. Zhang, W. Wei, R. Liu, Junle Qu, Y. Jiao, Robert H.Austin, andL. Liu, "Oriented collagen fibers direct tumor cell intravasation",Proc. Natl. Acad. Sci. USA(2016)

8. R. Liu, Y.Li, andL. Liu, "Single molecule fluorescence spectroscopy for quantitative biological applications",Quantitative Biology177–191 (2016)

9. G. Wang , X. Wang , T. Liu , R. Liu , andL. Liu, "In vitro experimental models and their molding technology of tumor cell",Acta. Phys. Sin.65,188700 (2016)

10. H. Wang, J. Liu, X. Zheng, X. Rong, X. Zheng, H. Peng, Z. S. Li, M. Li,L. Liu, "Three-dimensional virtual surgery models for percutaneous coronary intervention (PCI) optimization strategies",Sci. Rep.5,10945 (2015)

11. J. Zhu, L. Liang, Y. Jiao,L. Liu, "Enhanced Invasion of Metastatic Cancer Cells via Extracellular Matrix Interface",PLoS ONE10,1371 (2015)

12.L. Liu, G. Duclos, B. Sun, J. Lee, A. Wu, Y. Kam, E. D. Sontag, H. A. Stone, J. C. Sturm, R. A. Gatenby and R. H. Austin, "Minimization of thermodynamic costs in cancer cell invasion",Proc. Natl. Acad. Sci. USA10.1073 (2013)

13.L. Liu, B. Sun, K. Aw Yong, R. Getzenberg, H. Stone and R. Austin, “Probing the invasiveness of prostate cancer cells in a 3D microfabricated landscape”,Proc. Natl. Acad. Sci. USA108:6853–6856 (2011)（高亮文章）

14.L. Liu, K. Loutherback, D. Liao, D. Yeater, G. Lambert, A. Estevez-Torres, J. Sturm, R. Getzenberg and R. Austin, “A microfluidic device for continuous cancer cell culture and passage with hydrodynamic forces”,Lab on a Chip10, 1807-1813 (2010)

15.L. Liu, W. Cao, J. Wu, W. Wen, D. C. Chang and P. Sheng, “Design and Integration of an All-in-One Biomicrofluidic Chip”,Biomicrofluidics2,034103 (2008)

16.L. Liu, S. Peng, W. Wen and P. Sheng, “Micro Thermo Indicators and Optical-Electronic Temperature Control for Microfluidic Applications”,Appl. Phys. Lett. 91, 093513 (2007)

17.L. Liu, S. Peng, W. Wen and P. Sheng, “ Paperlike thermochromic display”,Appl. Phys. Lett.90 213508 (2007)

18.L. Liu, S. Peng, X. Niu and W. Wen, “Microheater fabricated from a conducting composite”,Appl. Phys. Lett.89, 223521 (2006)

19.L. Liu, X. Niu, W. Wen and P. Sheng, “Electrorheological fluid-actuated flexible platform”,Appl. Phys. Lett.88, 173505 (2006)

20.L. Liu, X. Chen, X. Niu, W. Wen, and P. Sheng, “Electrorheological fluid actuated microfluidic pump”,Appl. Phys. Lett.89, 083505 (2006)

21.L. Liu, X. Huang, C. Shen, Z. Liu, J. Shi, W. Wen and P. Sheng, “Parallel-field electrorheological clutch: Enhanced high shear rate performance”,Appl. Phys. Lett.87, 104106 (2005)^[1]