刘小华

刘小华：女，四川大学化学学院教授。

1996.9-2000.6，湖北师范学院化学系学习，获理学学士学位。

2000.9-2003.6，四川大学化学学院分析化学专业学习，获理学硕士学位。

2003.9-2006.6，四川大学化学学院有机化学专业学习，获理学博士学位。

2006.7-2010.6，四川大学化学学院副教授，硕士生导师。

2010.7-至今，四川大学化学学院教授。

2011年获教育部新世纪优秀人才计划资助。

2012年担任博士生导师。^[1]

主要从事不对称合成方法学及生理活性化合物的合成研究。

主要从事不对称合成方法学及生理活性化合物的合成研究。目前研究工作集中在新型手性双功能胍-酰xiān胺和胺类配体和催化剂的设计合成，基于双活化策略、胍基的碱性及氢键活化模式，在温和条件下，高效高选择性地实现了多个不对称催化反应。

作为第二完成人获2009年教育部自然科学奖一等奖和2012年国家自然科学二等奖。获国家自然科学基金委优秀青年基金和教育部新世纪优秀人才支持计划资助，获德国Thieme Chemistry Journals Award 2013。

（获奖成果、专著、论文、专利）

1. Shunxi Dong, Xiaohua Liu*, Yin Zhu, Peng He, Lili Lin, Xiaoming Feng*, Organocatalytic Oxyamination of Azlactones: Kinetic Resolution of Oxaziridines and Asymmetric Synthesis of Oxazolin-4-ones, J. Am. Chem. Soc. 2013, 135, 10026-10029.

2. Jing Wang, Xiaohua Liu*, Shunxi Dong, Lili Lin, Xiaoming Feng*, Asymmetric Organocatalytic Cyclopropanation of Cinnamone Derivatives with Stabilized Sulfonium Ylides, J. Org. Chem. 2013, 78, 6322-6327.

3. Zhenling Chen, Lili Lin, Min Wang, Xiaohua Liu*, Xiaoming Feng*, Asymmetric Synthesis of trans-β-Lactams by a Kinugasa Reaction on Water, Chem. Eur. J. 2013, 19, 7561–7567.

4. Min Wang, Xiaohua Liu*, Peng He, Lili Lin, Xiaoming Feng*, Enantioselective Synthesis of 1,2,4-Triazolines by Chiral Iron(II)-Complex Catalyzed Cyclization of α-Isocyano Esters and Azodicarboxylates, Chem. Commun. 2013, 49, 2572–2574.

5. Yang Yang, Shunxi Dong, Xiaohua Liu*, Lili Lin, Xiaoming Feng*, Chiral Guanidine-Catalyzed Asymmetric Direct Vinylogous Michael Reaction of α,β-Unsaturated γ-Butyrolactams with Alkylidene Malonates, Chem. Commun. 2012, 48, 5040–5042.

6. Yangbin Liu, Xiaohua Liu*, Min Wang, Peng He, Lili Lin, Xiaoming Feng*, Enantioselective Synthesis of 3,4-Dihydropyran Derivatives via Organocatalytic Michael Reaction of α,β-Unsaturated Enones, J. Org. Chem. 2012, 77, 4136–4142.

7. Xiao Xiao, Xiaohua Liu*, Shunxi Dong, Yunfei Cai, Lili Lin, Xiaoming Feng*, Asymmetric Synthesis of 2,3-Dihydroquinolin-4-one Derivatives Catalyzed by Chiral Bisguanidium Salt, Chem. Eur. J. 2012, 18, 15922–15925.

8. Xiaohua Liu, Lili Lin, Xiaoming Feng*, Chiral N,N'-Dioxides: New Ligands and Organocatalysts for Catalytic Asymmetric Reactions, Acc. Chem. Res. 2011, 44, 574–587.

9. Shunxi Dong, Xiaohua Liu*, Yulong Zhang, Lili Lin, and Xiaoming Feng*, Asymmetric Synthesis of 3,4-Diaminochroman-2-ones Promoted by Guanidine and Bisguanidium Salt, Org. Lett. 2011, 13, 5060–5063.

10. Jing Wang, Wentao Wang, Xiaohua Liu*, Zongrui Hou, Lili Lin, Xiaoming Feng*, Highly Enantioselective Direct Michael Addition of 1H-Benzotriazole to Chalcones Catalyzed by Sc(OTf)3/N,N-Dioxide Complex, Eur. J. Org. Chem. 2011, 2039–2042.

11. Xiaohong Chen, Shunxi Dong, Zhen Qiao, Yin Zhu, Mingsheng Xie, Lili Lin, Xiaohua Liu*, Xiaoming Feng*, Guanidine Organocatalyst for the Asymmetric Mannich-Type Reaction between α-Isothiocyanato Imide and Sulfonyl Imines, Chem. Eur. J. 2011, 17, 2583–2586.

12. Min Wang, Lili Lin, Jian Shi, Xiaohua Liu*, Yulong Kuang, Xiaoming Feng*, Asymmetric Crossed-Conjugate Addition of Nitroalkenes to Enones by a Chiral Bifunctional Diamine Organocatalyst, Chem. Eur. J. 2011, 17, 2365–2368.

13. Peng He, Xiaohua Liu*, Jian Shi, Lili Lin, Xiaoming Feng*, Organocatalytic Sequential Michael Reactions: Stereoselective Synthesis of Multifunctionalized Tetrahydroindan Derivatives, Org. Lett. 2011, 13, 936-939.

14. Zhenhua Dong, Xiaohua Liu*, Juhua Feng, Min Wang, Lili Lin, Xiaoming Feng*, Efficient Asymmetric Synthesis of 4H-Chromene Derivatives through a Tandem Michael Addition– Cyclization Reaction Catalyzed by a Salen–Cobalt(II) Complex, Eur. J. Org. Chem. 2011, 137–142.

15. Xuan Fu, Juhua Feng, Zhenhua Dong, Lili Lin, Xiaohua Liu*, Xiaoming Feng*, Enantioselective Synthesis of 2-Substituted-1,5-Benzodiazepines through Domino Reaction of o-Phenylenediamine and Chalcone Derivatives, Eur. J. Org. Chem. 2011, 5233–5236.

16. Yonghai Hui, Weiliang Chen, Wentao Wang, Jun Jiang, Yunfei Cai, Lili Lin, Xiaohua Liu*, Xiaoming Feng*, Highly Enantioselective Zinc-Catalyzed Friedel–Crafts Alkylation of Indoles with Ethyl Trifluoropyruvate, Adv. Synth. Catal. 2010, 352, 3174–3178.

17. Lin Zhou, Lili Lin, Wentao Wang, Jie Ji, Xiaohua Liu*, Xiaoming Feng*, Highly Enantioselective Michael Addition of Malonates to β,γ-Unsaturated α-Ketoesters Catalyzed by Chiral N,N'-dioxide-Yttrium(III) Complexes with Convenient Procedure, Chem. Commun. 2010, 46, 3601–3603.

18. Qi Zhang, Yonghai Hui, Xin Zhou, Lili Lin, Xiaohua Liu*, Xiaoming Feng*, Highly Efficient Asymmetric Three-Component Vinylogous Mannich Reaction Catalyzed by a Chiral Scandium(III)-N,N'-Dioxide Complex, Adv. Synth. Catal. 2010, 352, 976–980.

19. Xiaohua Liu, Lili Lin, Xiaoming Feng*, Amide Based Bifunctional Organocatalysts in Asymmetric Reactions (Feature Article), Chem. Commun. 2009, 6145–6158.

20. Xiaohua Liu, Bo Qin, Bin He, and Xiaoming Feng*, Catalytic Asymmetric Cyanosilylation of Ketones by a Chiral Amino Acid Salt, J. Am. Chem. Soc. 2005, 127, 12224-12225.

2012年获国家自然科学基金委优秀青年基金资助。

2013年入选四川省学术和技术带头人后备人选；获霍英东青年教师基金资助。

2015年获第二届中组部青年拔尖人才资助，享受国务院政府特殊津贴专家。

2016年获国家杰出青年科学基金资助。

2017年国家百千万人才工程入选者和有突出贡献中青年专家。

2018年入选四川省学术和技术带头人。

2020年获全国三八红旗手称号。

2021年当选英国皇家化学会会士。^[1]