冯鉴强,男,1949年4月出生,1973年毕业于中山医学院医疗系并留校任教。他现任中山大学中山医学院生理学教授和博士生导师。1988年获得医学博士学位,1993年至1995年在美国斯坦福大学医学中心医学院攻读博士后。
人物经历
1988年获医学博士学位,1993年至1995年在美国斯坦福大学医学中心医学院攻读博士后。
自1974年以来长期从事心血管生理学、神经生理学、分子生物学等方面的研究,培养了硕士生、博士生及博士后数十名。曾先后承担并完成国家教委、卫生部、广东省自然科学基金资助项目多项。
主要贡献
科研文献
1—5
Chen S L,Yang C T,Yang Z L,Guo R X,Meng J L,Cui Y,Lan A P,Chen P X,Feng J Q,Hydrogen Sulfide Protects H9c2 Cells Against Chemical Hypoxia-Induced Cell Injuries[J]. Clin Exp Pharmacol Physiol,2010,37 316-21.
[2]Guo R X,Zhang M,Liu W,Zhao C M,Cui Y,Wang C H,Feng J Q,Chen P X,NMDA receptors are involved in upstream of the spinal JNK activation in morphine antinociceptive tolerance[J]. Neurosci Lett,2009,467 ⑵:95-9.
Cui Y,Liao X X,Liu W,Guo R X,Wu Z Z,Zhao C M,Chen P X,Feng J Q,A novel role of minocycline: attenuating morphine antinociceptive tolerance by inhibition of p38 MAPK in the activated spinal microglia[J]. Brain Behav Immun,2008,22 ⑴:114-23.
[4]Tang X Q,Yang C T,Chen J,Yin W L,Tian S W,Hu B,Feng J Q,Li Y J,Effect of hydrogen sulphide on beta-amyloid-induced damage in PC12 cells[J]. Clin Exp Pharmacol Physiol,2008,35 ⑵:180-6.
Yu H M,Zhi J L,Cui Y,Tang E H,Sun S N,Feng J Q,Chen P X,Role of the JAK-STAT pathway in protection of hydrogen peroxide preconditioning against apoptosis induced by oxidative stress in PC12 cells[J]. Apoptosis,2006,11 ⑹:931-41.
6—10
Chen J,Tang X Q,Zhi J L,Cui Y,Yu H M,Tang E H,Sun S N,Feng J Q,Chen P X,Curcumin protects PC12 cells against 1-methyl-4-phenylpyridinium ion-induced apoptosis by bcl-2-mitochondria-ROS-iNOS pathway[J]. Apoptosis,2006,11 ⑹:943-53.
Cui Y,Chen Y,Zhi J L,Guo R X,Feng J Q,Chen P X,Activation of p38 mitogen-activated protein kinase in spinal microglia mediates morphine antinociceptive tolerance[J]. Brain Res,2006,1069 ⑴:235-43.
Liu W,Wang C H,Cui Y,Mo L Q,Zhi J L,Sun S N,Wang Y L,Yu H M,Zhao C M,Feng J Q,Chen P X,Inhibition of neuronal nitric oxide synthase antagonizes morphine antinociceptive tolerance by decreasing activation of p38 MAPK in the spinal microglia[J]. Neurosci Lett,2006,410 ⑶:174-7.
[9]Tang X Q,Yu H M,Zhi J L,Cui Y,Tang E H,Feng J Q,Chen P X,Inducible nitric oxide synthase and cyclooxgenase-2 mediate protection of hydrogen peroxide preconditioning against apoptosis induced by oxidative stress in PC12 cells[J]. Life Sci,2006,79 ⑼:870-6.
Tang X Q,Feng J Q,Chen J,Chen P X,Zhi J L,Cui Y,Guo R X,Yu H M,Protection of oxidative preconditioning against apoptosis induced by H2O2 in PC12 cells: mechanisms via MMP,ROS,and Bcl-2[J]. Brain Res,2005,1057 (1-2):57-64.
11—15
J.Feng and J.J.Kendig,Selective effects of alfentanil on nociceptive-related neurotransmission in neonatal rat spinal cord,British Journal of anaesthesia,1995,74:691-696
J.Feng and J.J.Kendig,N-Methy1-D-aspartate receptors are implicated in hyperresponsiveness following naloxone reversal of alfentanil in isolated rat spinal cord,Neuroscience Letters 189(1995)128-130
J.Feng and J.J.Kendig,The NMDA receptor antagonist MK-801 differentially modulates μ and κ opioid actions in spinal cord in vitro,Pain,1996,66:343-349
J.Feng and J.J.Kendig,Synergistic interactions between midazolam and alfentanil in isolated neonatal rat spinal cord,British Journal of Anaesthesia 1996;77:375-380
J.Feng and J.J.Kendig,Propofol potentiates the depressant effect of alfentanil in isolated neonatal rat spinal cord and blocks naloxone-precipitated hyperresponsiveness,Neuroscience Letters 1997,229:9-12
16—20
廖新学,杨春涛,杨战利,李建平,王礼春,黄雪,郭瑞鲜,陈培熹,冯鉴强,硫化氢对抗化学性缺氧引起的心肌细胞损伤及其机制[J].中国药理学通报,2009,25 ⑻:1012-7.
廖新学,郭瑞鲜,马虹,王礼春,陈正华,杨春涛,冯鉴强,血管紧张素-(1-7)对心肌缺血再灌注引起氧化应激及心功能变化的影响[J].南方医科大学学报,2008,28 ⑻:1345-8.
廖新学,孙胜楠,郭瑞鲜,张梅,王艳丽,陈培熹,冯鉴强,Jak-Stat通路调制NF-κb介导H2O2预处理的细胞保护作用[J].中国病理生理杂志,2008,24 ⑺:1422-7.
廖新学,唐小卿,郭瑞鲜,杨春涛,刘微,陈培熹,冯鉴强,ATP敏感钾通道在硫化氢钠对抗β-淀粉样肽诱导细胞损伤中的作用[J].中山大学学报:医学科学版,2008,29 ⑶:258-63.
廖新学,王艳丽,郭瑞鲜,孙胜楠,胡芬,陈培熹,冯鉴强,Erk1/2-Stat3通路在H2O2预处理导致的适应性细胞保护中的作用[J].中国病理生理杂志,2008,24 ⑼:1839-44.