仰大勇

仰大勇，男，天津大学化工学院教授、博士生导师、院长助理。^[1]

2002年和2005年，仰大勇分别于华中科技大学获得学士和硕士学位。2008年，他获得国家纳米科学中心博士学位。2010年，他在美国康奈尔大学和荷兰奈梅亨大学从事博士后研究。^[2]2021年4月1日，他在国家纳米科学中心南楼三层会议室作了题为《DNA：从生物分子到功能材料》的学术报告。^[3]2023年10月16日，他在武汉大学化学与分子科学学院电化学楼Z512会议室作了题为《DNA功能材料助力肿瘤诊疗》的报告。^[2]

1，Jianpu Tang+，Xuemei Jia+，Qian Li+，Zhen Cui，Aiqi Liang，Bin Ke，Dayong Yang*，Chi Yao*，A DNA-Based Hydrogel for Exosome Separation and Biomedical Applications. Proceedings of the National Academy of Sciences of the United States of America，2023，120，e2303822120.

2，Zhaoyue Lv+，Mengxue Huang+，Jing Yang+，Peiran Li，Lele Chang，Qianyun Tang，Xiaojing Chen，Shengqi Wang*，Chi Yao*，Peifeng Liu*，Dayong Yang*，A Smart DNA-based Nanosystem Containing Ribosome-Regulating siRNA for Enhanced mRNA Transfection. Advanced Materials，2023，2300823.

3，Chi Yao+,*，Yuwei Xu+，Jianpu Tang+，Pin Hu，Hedong Qi，Dayong Yang*，Dynamic Assembly of DNA-ceria Nanocomplex in Living Cells Generates Artificial Peroxisome. Nature Communications，2022，13，7739.

4，Chi Yao+，Junhan Ou+，Jianpu Tang+，Dayong Yang*，DNA Supramolecular Assembly on Micro/Nanointerfaces for Bioanalysis，Accounts of Chemical Research，2022，55，2043-2054.

6，Yuhang Dong+，Feng Li+，Zhaoyue Lv，Shuai Li，Meihe Yuan，Nachuan Song，Jinqiao Liu，Dayong Yang*，Lysosome Interference Enabled by Proton-Driven Dynamic Assembly of DNA Nanoframework inside Cells，Angewandte Chemie International Edition，2022，61，e202207770.

6，Feng Li+，Yujie Liu+，Yuhang Dong，Yiwen Chu，Nachuan Song，Dayong Yang*，Dynamic Assembly of DNA Nanostructures in Living Cells for Mitochondrial Interference，Journal of the American Chemical Society，2022，144，4667-4677.

7，Huaixin Zhao+，Linghui Li+，Feng Li*，Chunxia Liu，Mengxue Huang，Jiao Li，Feng Gao，Xinhua Ruan，Dayong Yang*，An Energy-Storing DNA-Based Nanocomplex for Laser-Free Photodynamic Therapy，Advanced Materials，2022，34，2109920.

8，Chi Yao+，Hedong Qi+，Xuemei Jia，Yuwei Xu，Zhaobin Tong，Zi Gu，Dayong Yang*，A DNA Nanocomplex Containing Cascade DNAzymes and Promoter-Like Zn-Mn-Ferrite for Combined Gene/Chemo-dynamic Therapy，Angewandte Chemie International Edition，2022，61，e202113619.

9，Jinpeng Han，Yanfei Guo，Hang Wang，Kunyu Zhang，Dayong Yang*，Sustainable Bioplastic Made from Biomass DNA and Ionomers，Journal of the American Chemical Society，2021，143，19486-19497.

10，Feng Li+，Nachuan Song+，Yuhang Dong，Shuai Li，Linghui Li，Yujie Liu，Zhemian Li，Dayong Yang*，A Proton-Activatable DNA-Based Nanosystem Enables Co-Delivery of CRISPR/Cas9 and DNAzyme for Combined Gene Therapy，Angewandte Chemie International Edition，2022，61，e202116569.

11，Chi Yao+，Chenxu Zhu+，Jianpu Tang，Junhan Ou，Rui Zhang，Dayong Yang*，T Lymphocyte-Captured DNA Network for Localized Immunotherapy，Journal of the American Chemical Society，2021，143，19330-19340.

12，Chi Yao+，Rui Zhang+，Jianpu Tang，Dayong Yang*，Rolling Circle Amplification (RCA)-Based DNA Hydrogel，Nature Protocols，2021，16，5460-5483.

13，Feng Li+，Zhaoyue Lv+，Xue Zhang，Yuhang Dong，Xiaohui Ding，Zhemian Li，Shuai Li，Chi Yao，Dayong Yang*，Supramolecular Self-Assembled DNA Nanosystem for Synergistic Chemical and Gene Regulations on Cancer Cells，Angewandte Chemie International Edition，2021，60，25557-25566.

14，Feng Li+，Wenting Yu+，Jiaojiao Zhang，Yuhang Dong，Xiaohui Ding，Xinhua Ruan，Zi Gu，Dayong Yang*，Spatiotemporally Programmable Cascade Hybridization of Hairpin DNA in Polymeric Nanoframework for Precise siRNA Delivery，Nature Communications，2021，12，1138.

15，Yuhang Dong+，Chi Yao+，Yi Zhu，Lu Yang，Dan Luo，Dayong Yang*，DNA Functional Materials Assembled from Branched DNA: Design，Synthesis and Applications，Chemical Reviews，2020，120，9420-9481.

16，Chi Yao+，Han Tang+，Weijian Wu，Jianpu Tang，Weiwei Guo，Dan Luo，Dayong Yang*，Double Rolling Circle Amplification Generates Physically Crosslinked DNA Network for Stem Cell Fishing，Journal of the American Chemical Society，2020，142，3422-3429.

17，Xiaocui Guo+，Feng Li+，Chunxia Liu，Yi Zhu，Nannan Xiao，Zi Gu，Dan Luo，Jianhui Jiang，Dayong Yang*，Construction of Organelle-Like Architecture by Dynamic DNA Assembly in Living Cells，Angewandte Chemie International Edition，2020，59，20651-20658.

18，Jianpu Tang+，Chi Yao+，Zi Gu，Sunghwan Jung，Dan Luo，Dayong Yang*，Super-Soft and Super-Elastic DNA Robot with Magnetically-Driven Navigational Locomotion for Cell Delivery in Confined Space，Angewandte Chemie International Edition，2020，59，2490-2495.

19，Xiaocui Guo+，Feng Li+，Lihui Bai，Wenting Yu，Xue Zhang，Yi Zhu，Dayong Yang*，Gene Circuit Compartment on Nanointerface Facilitatating Cascade Gene Expression，Journal of the American Chemical Society，2019，141，19171-19177.

20，Feng Li+，Jianpu Tang+，Jinhui Geng，Dan Luo，Dayong Yang*，Polymeric DNA Hydrogel: Design，Synthesis and Applications，Progress in Polymer Science，2019，98，101163.

参考资料：^[4]

1）DNA生物功能材料

2）肿瘤诊疗/食品安全检测

3）合成生物学

参考资料：^[5]

1）国家自然科学基金“杰出青年基金”

2）国家自然科学基金“优秀青年基金”

3）海外高层次人才计划

4）天津市杰青

5）国家重点研发计划

6）国家自然科学基金“面上项目”

参考资料：^[5]

中国生物医学工程学会纳米医学与工程分会委员、中国抗癌协会纳米肿瘤学专业委员会委员。^[1]