梁好均

梁好均（1963年5月-2022年2月11日），男，出生于吉林，中国科学技术大学高分子科学与工程系教授、博士生导师，合肥微尺度物质科学国家研究中心研究员。他在高分子材料设计、制备、高分子凝聚态物理和生物物理中的理论与计算等领域有着深入的研究。梁好均教授是2005年国家杰出青年基金获得者，同时也是The Open Chemical Physics Journal, International Journal of Polymer Science和《高分子学报》杂志的编委。2022年2月11日，梁好均在安徽合肥不幸逝世，享年59岁。^[1]

1984年7月毕业于东北师范大学物理系。

1990年12月在长春应用化学研究所获得博士学位。他的学术生涯中还包括多次海外访问学者经历。

1998年4月至2001年12月在中国科学技术大学担任高分子科学与工程系副教授。

1999年12月至2000年8月在香港中文大学化学系。

2000年12月至2001年9月在拉夫堡大学材料系。

2003年9月至11月在纽约州立大学布法罗分校生物物理系。

2002年起在中国科学技术大学担任高分子科学与工程系教授、博士生导师。

梁好均教授的研究集中在生物大分子设计、制备、高分子凝聚态物理和生物物理中的理论与计算等方面。他的实验工作主要集中在DNA组装及分子机器构建、DNA诱导的纳米粒子组装，以及基于分子机器的疾病诊断和生物传感。理论研究方面包括大分子粗粒化模型建立及多尺度模拟；DNA粗粒化模型构建及DNA组装的理论研究。梁教授先后承担了国家自然科学基金、国家973计划等研究课题，并在JACS, Macromolecules, J. Chem. Phys., J. Phys. Chem. B, Phys. Rev. E等期刊杂志上发表了120余篇SCI文章。他还是第十、十一届国家自然科学基金委高分子科学部评审专家。

梁好均教授主讲本科生课程《高分子链构象统计理论》和研究生课程《高分子凝聚态物理》。

梁好均教授的研究兴趣包括DNA分子机器及在疾病诊断中的应用、DNA大分子组装及生物传感器、高分子凝聚态物理理论计算与模拟。

DNA链替换反应调控细胞相互作用及细胞组装（国家自然科学基金重点项目，2021.01-）响应性高分子功能材料（国家自然科学基金创新研究群体项目，2021.01-）催组装新体系的构建：基元、催组剂和组装机理（国家自然科学基金重大项目子课题，2020.01-）DNA分子机器调控的"DNA tile"组装（国家自然科学基金面上项目，2016.01-2019.12）催组装体系的设计、构建与研究"（国家自然科学基金委员会"可控自组装体系及其功能化"重大研究计划，2015.01-2017.12）基于DNA链替换反应的DNA分子计算（国家自然科学基金重点项目，2015.01-2019.12）外场调控下嵌段共聚物及聚合物-无机纳米棒嵌段体的组装性能（国家自然科学基金委员会“可控自组装体系及其功能化”重大研究计划重点项目，2012.01-2015.12)高分子物理凝胶化机理、结构形成与功能调控（973国家重点基础研究发展计划子课题，2012.01-2016.12）DNA大分子链刚性与构象转变（国家自然科学基金重点项目，2010.01-2013.12）微囊藻毒素吸附树脂设计与制备（国家自然科学基金面上项目，2009.01-2011.12）两亲性嵌段聚合物在溶液中自组装的计算与模拟（国家自然科学基金面上项目，2008.01-2010.12）杂链大分子折叠、设计和自组装机理的研究（国家自然科学基金国际（地区）合作与交流项目，2008.12-2009.12）数学、计算机方法在高分子凝聚态、分子动态学方面的应用（国家杰出青年基金项目，2006.01-2009.12）高分子凝聚态介观、宏观尺度的理论和模拟（国家自然科学基金重大项目，2005.01-2008.12）溶剂挥发诱导下的嵌段聚合物组装行为（国家自然科学基金理论物理学及交叉科学重大研究计划面上项目，2005.01-2007.12）聚烯烃的多重结构及其高性能化的基础研究（973国家重点基础研究发展计划子课题，2005.12-2010.11）聚合物凝聚态微观、介观和宏观尺度的理论和模拟（国家自然科学基金重大项目子课题，2004.07-2008.06）大分子单链的相变和折叠（国家自然科学基金面上项目，2004.01-2006.12）多等距嵌段两亲性高分子构象研究（国家自然科学基金面上项目，2001.01-2003.12）^[2]

本硕衔接课程《高分子链构象统计学》研究生课程《高分子凝聚态物理》^[2]

Deng, M. G.; Jiang, Y.; Liang, H. J. Chen, J. Z. Y. Adsorption of a wormlike polymer in a potential well near a hard wall: Crossover between two scaling regimes, J. Chem. Phys. 2010, 133, 034902Deng, M. G.; Jiang, Y.; Li, X. J.; Wang, L.; Liang, H. J. Conformational behaviors of a charged-neutral star micelle in salt-free solution, Phys. Chem. Chem. Phys., 2010, 12, 6135Deng, M. G.; Jiang, Y.; Liang, H. J.; Chen J. Z. Y. Wormlike polymer brush: A self-consistent field treatment, Macromolecules,2010, 43, 3455He, P. T.; Li, X. J.; Deng, M. G.; Chen, T.; Liang, H. J. Complex micelles from the self-assembly of coil-rod-coil amphiphilic triblock copolymers in selective solvents, Soft Matt. 2010, 6, 1539He, P. T.; Li, X. J.; Kou, D. Z.; Deng, M. G.; Liang, H. J. Complex micelles from the self- assembly of amphiphilic triblock copolymers in selective solvents, J. Chem. Phys. 2010, 132, 204905Wang, L.; Liang, H. J.; Wu, J. Z. Electrostatic origins of polyelectrolyte adsorption: Theory and Monte Carlo simulations, J. Chem. Phys. 2010,133, 044906Yang ZY, et al., Translocation of alpha-helix chains through a nanopore, J Chem Phys, 2010, 133, 154903He LL, et al., Solvent-Induced Self-Assembly of Polymer-Tethered Nanorods, J Phys Chem, B, 2010, 114, 7189He LL，et al, Microphase transition of copolymer/nanorod composites under shear flow, Soft Matter, 2010, DOI: 10.1039/c0sm00703jChen, T.; Wang, L.; Lin, X. S.; Liu, Y.; Liang, H. J. Microcanonical analysis of adsorption of homopolymer chain on a surface; J. Chem. Phys. 2009, 130, 244905.Wang, L.; Chen, T.; Lin, X. S.; Liu, Y.; Liang, H. J. Canonical and microcanonical analysis of nongrafted homopolymer adsorption by an attractive substrate; J. Chem. Phys. 2009, 131, 244902Li, X. J.; Guo, J. Y.; Liu, Y.; Liang, H. J. Microphase separation of diblock copolymer poly(styrene-b-isoprene): A dissipative particle dynamics simulation study; J. Chem. Phys. 2009, 130, 074908.Li, X. J.; Pivkin, I. V.; Liang, H. J.; Karniadakis, G. E. Shape Transformations of Membrane Vesicles from Amphiphilic Triblock Copolymers: A Dissipative Particle Dynamics Simulation Study; Macromolecules 2009, 42, 3195.Li, X. J.; Liu, Y.; Wang, L.; Deng, M. G.; Liang, H. J. Fusion and fission pathways of vesicles from amphiphilic triblock copolymers: a dissipative particle dynamics simulation study; Phys. Chem. Chem. Phys. 2009, 11, 4051.Xu, B. S.; Yang, Y. D.; Liang, H. J.; Zhou, Y. Q. An all-atom knowledge-based energy function for protein-DNA threading, docking decoy discrimination, and prediction of transcription-factor binding profiles; Proteins 2009, 76, 718.Chen, J. Z. Y.; Liu, Y.; Liang, H. J. Structure of a Tubular Membrane Confining Spherical Particles; Phys. Rev. Lett. 2009, 102, 168103.He, L. L.; Zhang, L. X.; Xia, A.; Liang, H. J. Effect of nanorods on the mesophase structure of diblock copolymers; J. Chem. Phys. 2009, 130, 144907.Li, S. B.; Chen, P.; Wang, X. H.; Zhang, L. X.; Liang, H. J. Surface-induced morphologies of lamella-forming diblock copolymers confined in nanorod arrays; J. Chem. Phys. 2009, 130, 014902.Li, X. J.; Deng, M. G.; Liu, Y.; Liang, H. J. Dissipative Particle Dynamics Simulations of Toroidal Structure Formations of Amphiphilic Triblock Copolymers; J. Phys. Chem. B 2008, 112, 14762.Chen, P.; Liang, H. J.; Shi, A. C. Microstructures of a Cylinder-Forming Diblock Copolymer under Spherical Confinement; Macromolecules 2008, 41, 8938.Chen, P.; Liang, H.J.; Cylinder-forming triblock terpolymer in nanopores: A Monte Carlo simulation study; J. Phys. Chem. B 2008, 112, 1918.Chen, T.; Lin, X. S.; Liu, Y.; Lu, T.; Liang, H. J. Microcanonical analyses of homopolymer aggregation processes; Phys. Rev. E 2008, 78, 056101.He, L. L.; Zhang, L. X.; Liang, H. J. The effects of nanoparticles on the lamellar phase separation of diblock copolymers; J. Phys. Chem. B 2008, 112, 4194.Chen, P.; Liang, H. J.; Shi, A. C. Origin of microstructures from confined asymmetric diblock copolymers; Macromolecules 2007, 40, 7329.Chen, T.; Lin, X.; Liu, Y.; Liang, H. Microcanonical analysis of association of hydrophobic segments in a heteropolymer; Phys. Rev. E 2007, 76, 046110.Chen, P.; He, X. H.; Liang, H. J. Effect of surface field on the morphology of a symmetric diblock copolymer under cylindrical confinement; J. Chem. Phys. 2006, 124, 104906.Li, X. J.; Kou, D. Z.; Rao, S. L.; Liang, H. J. Developing a coarse-grained force field for the diblock copolymer poly(styrene-b-butadiene) from atomistic simulation; J. Chem. Phys. 2006, 124, 204909.Kou, D. Z.; Jiang, Y.; Liang, H. J. Microstructures from a mixture of ABC 3-miktoarm star terpolymers and homopolymers in two-dimensional space; J. Phys. Chem. B 2006, 110, 23557.Chen, P.; Liang, H. J. Monte Carlo simulations of cylinder-forming ABC triblock terpolymer thin films; J. Phys. Chem. B 2006, 110, 18212.Huang, R.; Jiang, Y.; Liang, H. J. Effect of architecture on the tensile properties of triblock copolymers in a lamellar phase; Chemphyschem 2006, 7, 1950.Li, X.; Jiang, Y.; Li, Y. C.; Liang, H. J. Influence of electric field on the phase transitions of the hexagonal cylinder phase of diblock copolymers; Chemphyschem 2006, 7, 1693.Jiang Y, Huang R.; Liang HJ Effect of polydispersity on the tensile modulus of diblock copolymers in a lamellar phase J. Chem. Phys. 2005, 123, 124906Jiang Y, Zhu JT, Jiang W & Liang HJ Cornucopian cylindrical aggregate morphologies from self-assembly of amphiphilic triblock copolymer in selective media J. Phys. Chem. B 2005, 109, 21549Zhu JT, Jiang Y, Liang HJ & Jiang W Self-assembly of ABA amphiphilic triblock copolymers into vesicles in dilute solution J. Phys. Chem. B. 2005, 109, 8619Jiang Y, Yan XY, Liang HJ & Shi AC Effect of polydispersity on the phase diagrams of linear ABC triblock copolymers in two dimensions J. Phys. Chem. B 2005, 109, 21047Jiang Y, Liang HJ & Shi AC Effect of polydispersity on the formation of vesicles from amphiphilic diblock copolymers Macromolecules 2005, 38, 6710Li XJ, Huang L & Liang HJ Developing coarse-grained force fields for cis-poly(1,4-butadiene) from the atomistic simulation Polymer 2005, 46, 6507Sun DC, Huang L & Liang HJ Unstable inverted phases of di- and tri-block copolymers on solution-casting films Macromolecules Research 2005, 13, 152Lu T, He XH & Liang HJ Ordered Microstructures by assembly of ABC 3-miktoarm star terpolymers and linear hompolymers J. Chem. Phys. 2004, 121, 9702Xu BS, Huang L & Liang HJ Thermodynamic behaviors of polyampholytes at low temperatures J. Chem. Phys. 2004, 121, 7494He XH, Liang HJ, Huang L & Pan CY Complex microstructures of amiphiphilic diblock copolymer in dilute solution J. Phys. Chem. B 2004, 108, 1731Dai B, Song M, Hourston DJ, He XH, Liang HJ & Pan CY Influence of block lengths and symmetries of block copolymers on phase behavior of polymer A/polymer B/block copolymer ternary blends Polymer, 2004, 45 1019Huang L, He XH, He TB & Liang HJ A cunning strategy in design of polymeric nanomaterials with novel microstructures J. Chem. Phys. 2003, 119, 12479Huang L, Xe XH, Wang YY, Chen HN & Liang HJ Phase transition of short chains at ultra low temperature J. Chem. Phys. 2003, 119, 2432He XH, Huang L, Liang HJ & Pan CY Localizations of junction points of ABC 3-miktoarm star terpolymers J. Chem. Phys. 2003, 118, 9861He XH, Liang HJ & Pan CY Self-condensing vinyl polymerization in the presence of multifunctional initiator with unequal rate constants: Monte Carlo simulation Polymer 2003, 44, 6697Huang L, He XH, Huang LS & Liang HJ Computer simulationon the self-assembly of associating polymers Polymer 2003, 44, 1967He XH, Huang L, Liang HJ & Pan CY Self-assebly of star block copolymers by dynamic density functional theory J. Chem. Phys. 2002, 116, 10508Liang HJ & Wang YY Influence of monomer types on the designability of a protein-model chain Chin. Phys. Lett. 2002, 19, 1382He XH, Liang HJ, Song M & Pan CY Possibility of design of nanodevices by confined macromolecular self-assembly Macromol. Theor Simul. 2002, 11, 379Wang YU, Chen HN, Liang HJ Monte Carlo simulation on the thermodynamic properties of a heteropolymer chain J. Chem. Phys. 2001, 115, 3951He XH, Song M, Liang HJ & Pan CY Self-assembly of the symmetric diblock copolymer in a confined state: Monte Carlo simulation. J. Chem. Phys. 2001,114, 10510He XH, Liang HJ & Pan CY Monte Carlo simulation of morphologies of self-assembled amphiphilic diblock copolymer in solution. Phys. Rev. E 2001, 63, 031804He XH, Liang HJ & Pan CY Monte Carlo simulation of hyperbranched copolymerizations in the presence of a multifunctional initiator Macromol. Theor Simul. 2001, 10, 196Liang HJ, Jiang W & He XH Monte Carlo simulation of pulsed-laser polymerization in emulsion Eur. Polym. J. 2000, 6, 2527Liang HJ & Chen HN First-order transition of a homopolymer chain with Lennard-Jones potential J. Chem. Phys. 2000, 113, 4469Liang HJ Designability of a protein chain in an off-lattice heteropolymer model J. Chem. Phys. 2000, 113, 4827Liang HJ, Li FH & He XH Monte Carlo simulation for the modification of polymer via grafting Eur. Polym. J. 2000, 36, 1613Liang HJ Observation of the molten globule state in a Monte Carlo simulation of the coil-to-globule transition of a homopolymer chain. J. Chem. Phys. 1999, 110, 10212Liang HJ Compatibility of triblock copolymers in an A/B/copolymer ternary mixture Macromolecules 1999, 32, 8204Liang HJ, He, XH, Jiang W & Jiang B. Monte Carlo simulation of phase separation of the A/B/A-B ternary mixture Macromol. Theory Simul. 1999, 8, 173

梁好均教授曾获得王宽诚育才奖（2003年，2012年）和国家杰出青年基金（2005年）。